Current Issue March 2012, Vol. 33, No. 3

Issue Highlights

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
March 2012(Vol. 33 | No. 3 | Pages 437-456)
Rita J. Guerreiro, Deborah R. Gustafson, John Hardy

Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease
March 2012(Vol. 33 | No. 3 | Pages 457-465)
Becky Inkster, Anil W. Rao, Khanum Ridler, Nicola Filippini, Brandon Whitcher, Thomas E. Nichols, Sally Wetten, Rachel A. Gibson, Michael Borrie, Andrew Kertesz, Danilo A. Guzman, Inge Loy-English, Julie Williams, Philipp G. Saemann, Dorothee P. Auer, Florian Holsboer, Federica Tozzi, Pierandrea Muglia, Emilio Merlo-Pich, Paul M. Matthews

Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease
March 2012(Vol. 33 | No. 3 | Pages 466-478)
Walter Koch, Stephan Teipel, Sophia Mueller, Jens Benninghoff, Maxmilian Wagner, Arun L.W. Bokde, Harald Hampel, Ute Coates, Maximilian Reiser, Thomas Meindl

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation
03 February 2012
Petroula Proitsi, Michelle K. Lupton, Frank Dudbridge, Magda Tsolaki, Gillian Hamilton, Makrina Daniilidou, Megan Pritchard, Kathryn Lord, Belinda M. Martin, David Craig, Stephen Todd, Bernadette McGuinness, Paul Hollingworth, Denise Harold, Iwona Kloszewska, Hilkka Soininen, Patrizia Mecocci, Bruno Velas, Michael Gill, Brian Lawlor, David C. Rubinsztein, Carol Brayne, Peter A. Passmore, Julie Williams, Simon Lovestone, John F. Powell
Abstract: Alzheimer's disease (AD) and age-related macular degeneration (AMD) are both neurodegenerative disorders which share common pathological and biochemical features of the complement pathway. T...
Acute moderate exercise enhances compensatory brain activation in older adults
03 February 2012
Kazuki Hyodo, Ippeita Dan, Kazuya Suwabe, Yasushi Kyutoku, Yuhki Yamada, Mitsuya Akahori, Kyeongho Byun, Morimasa Kato, Hideaki Soya
Abstract: A growing number of reports state that regular exercise enhances brain function in older adults. Recently a functional near-infrared spectroscopy (fNIRS) study revealed that an acute bout of...
Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea
03 February 2012
Chiemi Tanaka, Donald E. Coling, Senthilvelan Manohar, Guang-Di Chen, Bo Hua Hu, Richard Salvi, Donald Henderson
Abstract: The biological mechanisms that give rise to age-related hearing loss (ARHL) are still poorly understood. However, there is growing recognition that oxidative stress may be an important facto...
ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome
02 February 2012
Anne Grünewald, Björn Arns, Philip Seibler, Aleksandar Rakovic, Alexander Münchau, Alfredo Ramirez, Carolyn M. Sue, Christine Klein
Abstract: Mutations in ATP13A2 cause autosomal-recessive parkinsonism (Kufor-Rakeb syndrome; KRS). Because several other parkinsonism-associated proteins have been connected to mitochondrial function ...
Behavioral decay in aging male C. elegans correlates with increased cell excitability
30 January 2012
Xiaoyan Guo, Andrew Navetta, Daisy G. Gualberto, L. Rene García
Abstract: Deteriorative changes in behavioral functions are natural processes that accompany aging. In advanced aged C. elegans nematodes, gross decline in general behaviors, such as locomotion and fe...

View More Articles in Press...

Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
January 2011 (Vol. 32 | No. 1 | Pages 1-14)
Sarika Garg, Thomas Timm, Eva-Maria Mandelkow, Eckhard Mandelkow, Yipeng Wang
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
August 2010 (Vol. 31 | No. 8 | Pages 1275-1283)
Christopher C. Rowe, Kathryn A. Ellis, Miroslava Rimajova, Pierrick Bourgeat, Kerryn E. Pike, Gareth Jones, Jurgen Fripp, Henri Tochon-Danguy, Laurence Morandeau, Graeme O'Keefe, Roger Price, Parnesh Raniga, Peter Robins, Oscar Acosta, Nat Lenzo, Cassandra Szoeke, Olivier Salvado, Richard Head, Ralph Martins, Colin L. Masters, David Ames, Victor L. Villemagne
Metabolic syndrome, mild cognitive impairment, and progression to dementia. The Italian Longitudinal Study on Aging
November 2011 (Vol. 32 | No. 11 | Pages 1932-1941)
Vincenzo Solfrizzi, Emanuele Scafato, Cristiano Capurso, Alessia D’Introno, Anna Maria Colacicco, Vincenza Frisardi, Gianluigi Vendemiale, Marzia Baldereschi, Gaetano Crepaldi, Antonio Di Carlo, Lucia Galluzzo, Claudia Gandin, Domenico Inzitari, Stefania Maggi, Antonio Capurso, Francesco Panza, for the Italian Longitudinal Study on Aging Working Group
Automated MRI measures predict progression to Alzheimer's disease
August 2010 (Vol. 31 | No. 8 | Pages 1364-1374)
Rahul S. Desikan, Howard J. Cabral, Fabio Settecase, Christopher P. Hess, William P. Dillon, Christine M. Glastonbury, Michael W. Weiner, Nicholas J. Schmansky, David H. Salat, Bruce Fischl, Alzheimer's Disease Neuroimaging Initiative
The dynamics of Alzheimer's disease biomarkers in the Alzheimer's Disease Neuroimaging Initiative cohort
August 2010 (Vol. 31 | No. 8 | Pages 1263-1274)
A. Caroli, G.B. Frisoni, The Alzheimer's Disease Neuroimaging Initiative

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Ranked 3rd out of 44 journals in the ISI GERIATRICS & GERONTOLOGY category and 22nd out of 237 journals in the NEUROSCIENCES category!

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Neurobiology of Aging is published by Elsevier.

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About Neurobiology of Aging

Neurobiology of Aging publishes the results of studies in behavior, biochemistry, cell biology, endocrinology, molecular biology, morphology, neurology, neuropathology, pharmacology, physiology and protein chemistry in which the primary emphasis involves mechanisms of nervous system changes with age or diseases associated with age. Reviews and primary research articles are included, occasionally accompanied by open peer commentary. Letters to the Editor and brief communications are also acceptable. Brief reports of highly time-sensitive material are usually treated as rapid communications in which case editorial review is completed within six weeks and publication scheduled for the next available issue. The accepted abbreviation for Neurobiology of Aging for bibliographic citation is Neurobiol. Aging

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