Neurobiology of Aging
Volume 33, Issue 3 , Pages 588-602 , March 2012

Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation

  • Hyun Ju Lee

      Affiliations

    • Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    • Department of Physiology, Cell and Matrix Research, Institute, BSEI, World, Class University Program, School of Medicine, Kyungpook National University, Daegu, Korea
  • ,
  • Jong Kil Lee

      Affiliations

    • Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    • Department of Laboratory Animal Medicine, Cell and Matrix Research Institute, College of Veterinary Medicine, Kyungpook National University, Daegu, Korea
  • ,
  • Hyun Lee

      Affiliations

    • Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    • Department of Physiology, Cell and Matrix Research, Institute, BSEI, World, Class University Program, School of Medicine, Kyungpook National University, Daegu, Korea
  • ,
  • Janet E. Carter

      Affiliations

    • Department of Mental Health Sciences, Royal Free and University College Medical School, University College London, London, UK
  • ,
  • Jong Wook Chang

      Affiliations

    • Biomedical Research Institute, MEDIPOST Co., Ltd., Republic of Korea
  • ,
  • Wonil Oh

      Affiliations

    • Biomedical Research Institute, MEDIPOST Co., Ltd., Republic of Korea
  • ,
  • Yoon Sun Yang

      Affiliations

    • Biomedical Research Institute, MEDIPOST Co., Ltd., Republic of Korea
  • ,
  • Jun-Gyo Suh

      Affiliations

    • Department of Medical Genetics, College of Medicine, Hallym University, Chuncheon, Korea
  • ,
  • Byoung-Hee Lee

      Affiliations

    • Division of Biological Resources Coordination, National Institue of Biological Resources, Incheon, Korea
  • ,
  • Hee Kyung Jin

      Affiliations

    • Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    • Department of Laboratory Animal Medicine, Cell and Matrix Research Institute, College of Veterinary Medicine, Kyungpook National University, Daegu, Korea
    • Corresponding Author InformationCorresponding authors at: Kyungpook National University, Department of Physiology, School of Medicine, 101 Dongindong 2 Ga, Jung-Gu, Daegu 700-422, Republic of Korea; College of Veterinary Medicine, Kyungpook National University, Sankyuk 3-dong, Buk-gu, Daegu 702-701, Republic of Korea. Tel.: +82 53 420 4815, 82 53 950 5966; fax: +82 53 424 3349, 82 53 950 5955
  • ,
  • Jae-sung Bae

      Affiliations

    • Stem Cell Neuroplasticity Research Group, Kyungpook National University, Daegu, Korea
    • Department of Physiology, Cell and Matrix Research, Institute, BSEI, World, Class University Program, School of Medicine, Kyungpook National University, Daegu, Korea
    • Corresponding Author InformationCorresponding authors at: Kyungpook National University, Department of Physiology, School of Medicine, 101 Dongindong 2 Ga, Jung-Gu, Daegu 700-422, Republic of Korea; College of Veterinary Medicine, Kyungpook National University, Sankyuk 3-dong, Buk-gu, Daegu 702-701, Republic of Korea. Tel.: +82 53 420 4815, 82 53 950 5966; fax: +82 53 424 3349, 82 53 950 5955

Received 1 October 2009 ,Revised 26 March 2010 ,Accepted 31 March 2010.

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PII: S0197-4580(10)00157-0

doi: 10.1016/j.neurobiolaging.2010.03.024

Neurobiology of Aging
Volume 33, Issue 3 , Pages 588-602 , March 2012