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Neurobiology of Aging
Volume 32, Issue 12
, Pages 2279-2286
, December 2011
Running reduces stress and enhances cell genesis in aged mice
References
- . Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 1999;96:5280–5285
- . Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc. Natl. Acad. Sci. U.S.A. 1998;95:15020–15025
- . Early age-related changes in adult hippocampal neurogenesis in C57 mice. Neurobiol. Aging. 2010;31:151–161
- . Exercise increases neural stem cell number in a growth hormone-dependent manner, augmenting the regenerative response in aged mice. Stem Cells. 2009;27:2044–2052
- . Restoring production of hippocampal neurons in old age. Nat. Neurosci. 1999;2:894–897
- . Aerobic fitness reduces brain tissue loss in aging humans. J. Gerontol. A: Biol. Sci. Med. Sci. 2003;58:176–180
- . Running enhances spatial pattern separation in mice. Proc. Natl. Acad. Sci. U.S.A. 2010;www.pnas.org/cgi/doi/10.1073/pnas.0911725107
- . Effects of long-term voluntary exercise on the mouse hypothalamic-pituitary-adrenocortical axis. Endocrinology. 2003;144(7):3012–3023
- . Distinct, time-dependent effects of voluntary exercise on circadian and ultradian rhythms and stress responses of free corticosterone in the rat hippocampus. Endocrinology. 2009;150(9):4170–4179
- . Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density. J. Comp. Neurol. 2005;486(1):39–47
- . Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience. 2004;124:71–79
- . Structural synaptic plasticity associated with the induction of long-term potentiation is preserved in the dentate gyrus of aged rats. Hippocampus. 1992;2:445–456
- . Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc. Natl. Acad. Sci. U.S.A. 1998;95:3168–3171
- . The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch. Phys. Med. Rehabil. 2004;85:1694–1704
- . New pharmacological strategies for cognitive enhancement using a rat model of age-related memory impairment. Ann. N. Y. Acad. Sci. 1994;717:16–32
- . Stress differentially regulates the effects of voluntary exercise on cell proliferation in the dentate gyrus of mice. Hippocampus. 2008;19:889–897
- . Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus. Nat. Neurosci. 2007;10:355–362
- . More hippocampal neurons in adult mice living in an enriched environment. Nature. 1997;386:493–495
- . Age-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats. Neurosci. Lett. 2004;355:152–154
- . Exercise, cognition, and the aging brain. J. Appl. Physiol. 2006;101:1237–1242
- . Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiol. Aging. 2006;27:1505–1513
- . Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 1996;16:2027–2033
- . Hippocampal volumes in Alzheimer's disease, Parkinson's disease with and without dementia, and in vascular dementia: an MRI study. Neurology. 1996;46:678–681
- . Basal cortisol levels and cognitive deficits in human aging. J. Neurosci. 1994;14:2893–2903
- . Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nat. Neurosci. 1998;1:69–73
- . Circadian pattern of total and free corticosterone concentrations, corticosteroid-binding globulin, and physical activity in mice selectively bred for high voluntary wheel-running behavior. Gen. Comp. Endocrinol. 2008;156:210–217
- . Extended voluntary running inhibits exercise-induced adult hippocampal progenitor proliferation in the spontaneously hypertensive rat. J. Neurophysiol. 2005;93:2406–2414
- . Environmental enrichment improves cognitive deficits in spontaneously hypertensive rats (SHR): relevance for attention deficit/hyperactivity disorder (ADHD). Prog. Neuropsychopharmacol. Biol. Psychiatry. 2009;33:1153–1160
- . Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus. Neuroscience. 2006;137:1299–1307
- . Physical activity and Alzheimer's disease: from prevention to therapeutic perspectives. J. Am. Med. Dir. Assoc. 2008;9:390–405
- . Do glucocorticoid concentrations rise with age in the rat?. Neurobiol. Aging. 1992;13:171–174
- . Inhibition of glucocorticoid secretion by the hippocampal formation in the primate. J. Neurosci. 1991;11:3695–3704
- . Adult-born hippocampal neurons are more numerous, faster maturing, and more involved in behavior in rats than in mice. J. Neurosci. 2009;29:14484–14495
- . Social isolation delays the positive effects of running on adult neurogenesis. Nat. Neurosci. 2006;9:526–533
- . Stress inhibits the proliferation of granule cell precursors in the developing dentate gyrus. Int. J. Dev. Neurosci. 1998;16:235–239
- . Preference for social contact versus environmental enrichment in male laboratory mice. Lab. Anim. 2004;38:178–188
- . Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 1999;2:266–270
- . Functional neurogenesis in the adult hippocampus. Nature. 2002;415:1030–1034
- . Exercise enhances learning and hippocampal neurogenesis in aged mice. J. Neurosci. 2005;25:8680–8685
- . Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex. J. Neurochem. 2005;93:1434–1443
PII: S0197-4580(10)00010-2
doi: 10.1016/j.neurobiolaging.2009.12.025
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Neurobiology of Aging
Volume 32, Issue 12
, Pages 2279-2286
, December 2011
