Neurobiology of Aging
Volume 32, Issue 9 , Pages 1716-1724 , September 2011

F1 (CBA×C57) mice show superior hearing in old age relative to their parental strains: Hybrid vigor or a new animal model for “Golden Ears”?

  • Robert D. Frisina

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • Department of Neurobiology & Anatomy and Biomedical Engineering, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA
    • Corresponding Author InformationCorresponding author at: Otolaryngology Dept., Univ. Rochester Medical School, 601 Elmwood Avenue, Rochester, NY 14642-8629, USA. Tel.: +1 585 275 8130; fax: +1 585 271 8552.
    • ,
  • Ameet Singh

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA
    • ,
  • Matthew Bak

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA
    • ,
  • Sara Bozorg

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA
    • ,
  • Rahul Seth

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA
    • ,
  • Xiaoxia Zhu

      Affiliations

    • Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    • International Center for Hearing & Speech Research – National Technical Institute for Deaf, Rochester Inst. Technology, Rochester, NY 14623, USA

Received 24 June 2009 ,Revised 17 September 2009 ,Accepted 27 September 2009.

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☆ Grant Support: NIH Grant P01 AG09524 from the National Institute on Aging, and NIH Grant P30 DC05409 from the National Institute on Deafness & Communication Disorders.

PII: S0197-4580(09)00315-7

doi: 10.1016/j.neurobiolaging.2009.09.009

Neurobiology of Aging
Volume 32, Issue 9 , Pages 1716-1724 , September 2011

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