« Previous
Next »
Neurobiology of Aging
Volume 31, Issue 4
, Pages 542-548
, April 2010
Molecular polymorphism of Aβ in Alzheimer's disease
References
- . Insights into prion strains and neurotoxicity. Nat. Rev. Mol. Cell. Biol. 2007;8(7):552–561
- . Studies of luminescent conjugated polythiophene derivatives: enhanced spectral discrimination of protein conformational states. Bioconjug. Chem. 2007;18(4):1860–1868
- . Amyloid beta peptide 1–42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology. Acta Neuropathol. (Berl.). 2004;107(4):283–291
- . Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology. 2006;66(12):1837–1844
- . Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch. Neurol. 1995;52(1):81–88
- . Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging. Bioorg. Med. Chem. Lett. 2006;16(5):1350–1352
- . A general model of prion strains and their pathogenicity. Science. 2007;318(5852):930–936
- . Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology. 1988;38(11):1682–1687
- . Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behav. Gen. 2007;37(1):79–100
- . In vitro characterization of Pittsburgh compound-B binding to Lewy bodies. J. Neurosci. 2007;27(39):10365–10371
- Forsberg, A., Engler, H., Almkvist, O., Blomquist, G., Hagman, G.,Wall, A., Ringheim, A., Langstrom, B., Nordberg, A., 2007. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol. Aging, doi:10.1016/j.neurobiolaging.2007.03.029, in press.
- . The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297(5580):353–356
- . Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody. Lab. Invest. 1989;60(1):113–122
- . Post-mortem correlates of in vivo PIB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain. 2008;131(6):1630–1645
- . Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann. Neurol. 2007;
- . APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques. Biochemistry. 2002;41(3):922–928
- . Conformation-dependent anti-amyloid oligomer antibodies. Methods Enzymol. 2006;413:326–344
- . Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Mol. Neurodegener. 2007;2(1):18
- . PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment. Neurology. 2007;68(19):1603–1606
- . Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann. Neurol. 2004;55(3):306–319
- . Amyloid deposits in transgenic PS1/APP mice do not bind the amyloid PET tracer, PIB, in the same manner as human brain amyloid. Neurobiol. Aging. 2004;25(S2):232
- . The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J. Neurosci. 2003;23(6):2086–2092
- Kung, M.P., Hou., C., Zhuang, Z.P., Cross, A.J., Maier, D.L., Kung, H.F., 2004. Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice. Eur. J. Nucl. Med. Mol. Imag. (10.1007/S00259-004-1487-z).
- . IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques. Brain Res. 2002;956(2):202–210
- . Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains. J. Biol. Chem. 2001;276(16):12991–12998
- . Monoclonal antibodies that target pathological assemblies of Abeta. J. Neurochem. 2007;100(1):23–35
- . Y10W beta(1–40) fluorescence reflects epitope exposure in conformers of Alzheimer's beta-peptide. Arch. Biochem. Biophys. 2003;417(1):112–122
- . Multiple ligand binding sites on A beta(l–40) fibrils. Amyloid. 2005;12(1):5–14
- . Chapter 11. Models of Alzheimer's disease. In: Conn MP editors. Handbook of Models for Human Aging. New York, NY: Academic Press/Elsevier; 2006;p. 121–134
- . Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nucl. Magn. Reson. 2006;29(1–3):183–190
- . PIB is a non-specific imaging marker of amyloid-beta (A{beta}) peptide-related cerebral amyloidosis. Brain. 2007;130(10):2607–2610
- . Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils. J. Biol. Chem. 2005;280(9):7677–7684
- . Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography. J. Neurosci. 2007;27(41):10957–10968
- . A pH-dependent conformational transition of Abeta peptide and physicochemical properties of the conformers in the glial cell. Biochem. J. 2002;361(Pt 3):547–556
- . Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science. 2006;313(5794):1781–1784
- . Humoral immune response to fibrillar beta-amyloid peptide. Biochemistry. 2003;42(40):11682–11692
- . Aβ solubility and deposition during AD progression and in APPXPS1 Knock-in mice. Neurobiol. Dis. 2007;
- . Imaging distinct conformational states of amyloid-beta fibrils in Alzheimer's disease using novel luminescent probes. ACS Chem. Biol. 2007;2(8):553–560
- . Conformational antibodies recognizing a generic amyloid fibril epitope. Proc. Natl. Acad. Sci. U.S.A. 2002;99(3):1485–1490
- . Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science. 2005;307(5707):262–265
- . Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils. Biochemistry. 2006;45(2):498–512
- . 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology. 2007;68(15):1205–1212
- . PIB binding in Alzheimer's disease and nonhuman primate brain. In: Proceedings of the 11th International Conference on Alzheimer's Disease and Related Disorders. Chicago, IL. 2008;
- . Host and transmissible spongiform encephalopathy agent strain control glycosylation of PrP. J. Gen. Virol. 1999;80(Pt 7):1865–1872
- . Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals. Neurosci. Lett. 1988;93(2–3):191–196
- . The structural basis of yeast prion strain variants. Nature. 2007;449(7159):233–237
- . Koch's postulates and infectious proteins. Acta Neuropathol. 2006;112(1):1–4
- . The state of the prion. Nat. Rev. Microbiol. 2004;2(11):861–871
- . Plasticity of amyloid fibrils. Biochemistry. 2007;46(1):1–10
- . Plaques, tangles and dementia. A quantitative study. J. Neurol. Sci. 1982;56(2–3):343–356
- . Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease. Acta Neuropathol. (Berl.). 1989;78(4):337–347
- . Visualization and classification of amyloid beta supramolecular assemblies. Biochemistry. 2007;46(51):15009–15017
- . A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining. Acta Neuropathol. 1988;76(6):541–549
- . Delineation of PET imaging agent binding sites on beta -amyloid peptide fibrils. J. Biol. Chem. 2005;280(25):23599–23604
- . Pore-forming proteins share structural and functional homology with amyloid oligomers. Neuromol. Med. 2007;9(3):270–275
- . The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathol. 2006;16(1):30–39
PII: S0197-4580(08)00182-6
doi: 10.1016/j.neurobiolaging.2008.05.026
© 2008 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 31, Issue 4
, Pages 542-548
, April 2010
