Neurobiology of Aging
Volume 29, Issue 8 , Pages 1133-1136, August 2008

Neurofibrillary changes of the Alzheimer type in very elderly individuals: Neither inevitable nor benign:

Commentary on “No disease in the brain of a 115-year-old woman”

Institute for Clinical Neuroanatomy, Theodor Stern Kai 7, 60590 Frankfurt/Main, Germany

Received 24 April 2008; accepted 24 April 2008. published online 10 June 2008.

Keywords: Aging, Centenarians, Neurofibrillary tangles, Neuropil threads, Staging, Supercentenarians

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PII: S0197-4580(08)00143-7

doi:10.1016/j.neurobiolaging.2008.04.016

Neurobiology of Aging
Volume 29, Issue 8 , Pages 1133-1136, August 2008