Neurobiology of Aging
Volume 31, Issue 3 , Pages 378-386 , March 2010

Brain tissue volumes in relation to cognitive function and risk of dementia

  • M. Arfan Ikram

      Affiliations

    • Department of Epidemiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Henri A. Vrooman

      Affiliations

    • Department of Radiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
    • Department of Medical Informatics, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Meike W. Vernooij

      Affiliations

    • Department of Epidemiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Tom den Heijer

      Affiliations

    • Department of Epidemiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
    • Department of Neurology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Albert Hofman

      Affiliations

    • Department of Epidemiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Wiro J. Niessen

      Affiliations

    • Department of Radiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
    • Department of Medical Informatics, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Aad van der Lugt

      Affiliations

    • Department of Radiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Peter J. Koudstaal

      Affiliations

    • Department of Neurology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
  • ,
  • Monique M.B. Breteler

      Affiliations

    • Department of Epidemiology, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 10 7043489; fax: +31 10 7044657.

Received 7 February 2008 ,Revised 25 March 2008 ,Accepted 9 April 2008.

References 

  1. Anbeek P, Vincken KL, van Bochove GS, van Osch MJ, van der Grond J. Probabilistic segmentation of brain tissue in MR imaging. Neuroimage. 2005;27(4):795–804
  2. Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol. Aging. 2004;25(1):5–18(author reply 49–62)
  3. Bleecker ML, Bolla-Wilson K, Agnew J, Meyers DA. Age-related sex differences in verbal memory. J. Clin. Psychol. 1988;44:403–411
  4. Blennow K, de Leon MJ, Zetterberg H. Alzheimer's disease. Lancet. 2006;368(9533):387–403
  5. Bobinski M, de Leon MJ, Wegiel J, Desanti S, Convit A, Saint Louis LA, et al. The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience. 2000;95(3):721–725
  6. Bokde AL, Teipel SJ, Zebuhr Y, Leinsinger G, Gootjes L, Schwarz R, et al. A new rapid landmark-based regional MRI segmentation method of the brain. J. Neurol. Sci. 2002;194(1):35–40
  7. Bokde AL, Teipel SJ, Schwarz R, Leinsinger G, Buerger K, Moeller T, et al. Reliable manual segmentation of the frontal, parietal, temporal, and occipital lobes on magnetic resonance images of healthy subjects.. Brain Res. Brain Res. Protoc. 2005;14(3):135–145
  8. Braak H, Braak E, Bohl J. Staging of Alzheimer-related cortical destruction. Eur. Neurol. 1993;33(6):403–408
  9. Breteler MM, van Amerongen NM, van Swieten JC, Claus JJ, Grobbee DE, van Gijn J, et al. Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study. Stroke. 1994;25(6):1109–1115
  10. Chetelat G, Baron JC. Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging. Neuroimage. 2003;18(2):525–541
  11. de Leon MJ, Convit A, DeSanti S, Golomb J, Tarshish C, Rusinek H, et al The hippocampus in aging and Alzheimer's disease. Neuroimag. Clin. N. Am. 1995;5(1):1–17
  12. Deary IJ, Bastin ME, Pattie A, Clayden JD, Whalley LJ, Starr JM, et al. White matter integrity and cognition in childhood and old age. Neurology. 2006;66(4):505–512
  13. DeCarli C. Mild cognitive impairment: prevalence, prognosis, aetiology, and treatment. Lancet Neurol. 2003;2(1):15–21
  14. DeCarli C, Massaro J, Harvey D, Hald J, Tullberg M, Au R, et al. Measures of brain morphology and infarction in the framingham heart study: establishing what is normal. Neurobiol. Aging. 2005;26(4):491–510
  15. Delacourte A, David JP, Sergeant N, Buee L, Wattez A, Vermersch P, et al. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease. Neurology. 1999;52(6):1158–1165
  16. den Heijer T, Geerlings MI, Hoebeek FE, Hofman A, Koudstaal PJ, Breteler MM. Use of hippocampal and amygdalar volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people. Arch. Gen. Psychiatry. 2006;63(1):57–62
  17. Erten-Lyons D, Howieson D, Moore MM, Quinn J, Sexton G, Silbert L, et al. Brain volume loss in MCI predicts dementia. Neurology. 2006;66(2):233–235
  18. Fernando MS, Simpson JE, Matthews F, Brayne C, Lewis CE, Barber R, et al. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke. 2006;37(6):1391–1398
  19. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 1975;12(3):189–198
  20. Fotenos AF, Snyder AZ, Girton LE, Morris JC, Buckner RL. Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD. Neurology. 2005;64(6):1032–1039
  21. Fox NC, Crum WR, Scahill RI, Stevens JM, Janssen JC, Rossor MN. Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images. Lancet. 2001;358(9277):201–205
  22. Geerlings MI, Jonker C, Bouter LM, Ader HJ, Schmand B. Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition. Am. J. Psychiatry. 1999;156(4):531–537
  23. Halliday GM, Double KL, Macdonald V, Kril JJ. Identifying severely atrophic cortical subregions in Alzheimer's disease. Neurobiol. Aging. 2003;24(6):797–806
  24. Hofman A, Breteler MM, van Duijn CM, Krestin GP, Pols HA, Stricker BH, et al. The Rotterdam Study: objectives and design update. Eur. J. Epidemiol. 2007;22(11):819–829
  25. Houx PJ, Jolles J, Vreeling FW. Stroop interference: aging effects assessed with the Stroop Color-Word Test. Exp. Aging Res. 1993;19(3):209–224
  26. Ikram MA, Vrooman HA, Vernooij MW, van der Lijn F, Hofman A, van der Lugt A, et al. Brain tissue volumes in the general elderly population. The Rotterdam Scan Study. Neurobiol. Aging. 2008;29(6):882–890
  27. Jack CR, Petersen RC, Xu YC, O’Brien PC, Smith GE, Ivnik RJ, et al. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology. 1999;52(7):1397–1403
  28. Jack CR, Dickson DW, Parisi JE, Xu YC, Cha RH, O’Brien PC, et al. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology. 2002;58(5):750–757
  29. Jack CR, Shiung MM, Gunter JL, O’Brien PC, Weigand SD, Knopman DS, et al. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD. Neurology. 2004;62(4):591–600
  30. Jack CR, Shiung MM, Weigand SD, O’Brien PC, Gunter JL, Boeve BF, et al. Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI. Neurology. 2005;65(8):1227–1231
  31. Killiany RJ, Gomez-Isla T, Moss M, Kikinis R, Sandor T, Jolesz F, et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann. Neurol. 2000;47(4):430–439
  32. Klein S, Staring M, Pluim JP. Comparison of gradient approximation techniques for optimisation of mutual information in nonrigid registration. Medical imaging: image process. Proc. SPIE. 2005;5747:192–203
  33. Lezak MD, Howieson DB, Loring DW. Neuropsychological Assessment. New York, NY: Oxford University Press; 2004;
  34. Longstreth WT, Arnold AM, Manolio TA, Burke GL, Bryan N, Jungreis CA, et al. Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Collaborative Research Group. Neuroepidemiology. 2000;19(1):30–42
  35. Mortimer JA, Gosche KM, Riley KP, Markesbery WR, Snowdon DA. Delayed recall, hippocampal volume and Alzheimer neuropathology: findings from the Nun Study. Neurology. 2004;62(3):428–432
  36. Mosley TH, Knopman DS, Catellier DJ, Bryan N, Hutchinson RG, Grothues CA, et al. Cerebral MRI findings and cognitive functioning: the Atherosclerosis Risk in Communities study. Neurology. 2005;64(12):2056–2062
  37. Mungas D, Jagust WJ, Reed BR, Kramer JH, Weiner MW, Schuff N, et al. MRI predictors of cognition in subcortical ischemic vascular disease and Alzheimer's disease. Neurology. 2001;57(12):2229–2235
  38. Mungas D, Harvey D, Reed BR, Jagust WJ, DeCarli C, Beckett L, et al. Longitudinal volumetric MRI change and rate of cognitive decline. Neurology. 2005;65(4):565–571
  39. Ott A, Breteler MM, van Harskamp F, Stijnen T, Hofman A. Incidence and risk of dementia. The Rotterdam Study. Am. J. Epidemiol. 1998;147(6):574–580
  40. Prins ND, van Dijk EJ, den Heijer T, Vermeer SE, Jolles J, Koudstaal PJ, et al. Cerebral small-vessel disease and decline in information processing speed, executive function and memory. Brain. 2005;128(Pt 9):2034–2041
  41. Roth M, Tym E, Mountjoy CQ, Huppert FA, Hendrie H, Verma S, et al. CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br. J. Psychiatry. 1986;149:698–709
  42. Rueckert D, Sonoda LI, Hayes C, Hill DL, Leach MO, Hawkes DJ. Nonrigid registration using free-form deformations: application to breast MR images. IEEE Trans. Med. Imaging. 1999;18(8):712–721
  43. Scheltens P, Barkhof F, Leys D, Wolters EC, Ravid R, Kamphorst W. Histopathologic correlates of white matter changes on MRI in Alzheimer's disease and normal aging. Neurology. 1995;45(5):883–888
  44. Shenkin SD, Bastin ME, Macgillivray TJ, Deary IJ, Starr JM, Rivers CS, et al. Cognitive correlates of cerebral white matter lesions and water diffusion tensor parameters in community-dwelling older people. Cerebrovasc. Dis. 2005;20(5):310–318
  45. Smith CD, Chebrolu H, Wekstein DR, Schmitt FA, Jicha GA, Cooper G, et al. Brain structural alterations before mild cognitive impairment. Neurology. 2007;68(16):1268–1273
  46. Soderlund H, Nilsson LG, Berger K, Breteler MM, Dufouil C, Fuhrer R, et al. Cerebral changes on MRI and cognitive function: the CASCADE study. Neurobiol. Aging. 2006;27(1):16–23
  47. Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, et al. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann. Neurol. 2007;62(4):406–413
  48. Swan GE, DeCarli C, Miller BL, Reed T, Wolf PA, Carmelli D. Biobehavioral characteristics of nondemented older adults with subclinical brain atrophy. Neurology. 2000;54(11):2108–2114
  49. van Oijen M, De Jong FJ, Hofman A, Koudstaal PJ, Breteler MM. Subjective memory complaints, education, and risk of Alzheimer's disease. Alzheimer's Dementia. 2007;3(2):92–97
  50. Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM. Silent brain infarcts and the risk of dementia and cognitive decline. N. Engl. J. Med. 2003;348(13):1215–1222
  51. Vrooman HA, Cocosco CA, van der Lijn F, Stokking R, Ikram MA, Vernooij MW, et al. Multi-spectral brain tissue segmentation using automatically trained k-nearest-neighbor classification. Neuroimage. 2007;37(1):71–81
  52. Welsh KA, Butters N, Mohs RC, Beekly D, Edland S, Fillenbaum G, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology. 1994;44(4):609–614
  53. Whitwell JL, Weigand SD, Shiung MM, Boeve BF, Ferman TJ, Smith GE, et al. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain. 2007;130(Pt 3):708–719
  54. WHO . 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. Guidelines Subcommittee. J. Hypertens. 1999;17(2):151–183
  55. Wolf H, Hensel A, Kruggel F, Riedel-Heller SG, Arendt T, Wahlund LO, et al. Structural correlates of mild cognitive impairment. Neurobiol. Aging. 2004;25(7):913–924

PII: S0197-4580(08)00133-4

doi: 10.1016/j.neurobiolaging.2008.04.008

Neurobiology of Aging
Volume 31, Issue 3 , Pages 378-386 , March 2010