Neurobiology of Aging
Volume 30, Issue 11 , Pages 1724-1727 , November 2009

Midlife C-reactive protein and risk of cognitive decline: A 31-year follow-up

  • Danielle Laurin

      Affiliations

    • Laval University Geriatrics Research Unit, Centre de recherche du CHA, and Faculty of Pharmacy, Laval University, 1050 Chemin Sainte-Foy, Local L2-30, Quebec City, Quebec G1S 4L8, Canada
    • Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Gateway Building, Room 3C309, Bethesda, MD 20892-9205, USA
    • Tel.: +1 418 682 7511x4832.
    • ,
  • J. David Curb

      Affiliations

    • Pacific Health Research Institute, and Kuakini Medical Center, 846 South Hotel Street, Suite 301, Honolulu, HI 96813, USA
    • Tel.: +1 808 524 4411.
    • ,
  • Kamal H. Masaki

      Affiliations

    • Pacific Health Research Institute, and Kuakini Medical Center, 846 South Hotel Street, Suite 301, Honolulu, HI 96813, USA
    • Tel.: +1 808 524 4411.
    • ,
  • Lon R. White

      Affiliations

    • Pacific Health Research Institute, and Kuakini Medical Center, 846 South Hotel Street, Suite 301, Honolulu, HI 96813, USA
    • Tel.: +1 808 524 4411.
    • ,
  • Lenore J. Launer

      Affiliations

    • Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Gateway Building, Room 3C309, Bethesda, MD 20892-9205, USA
    • Tel.: +1 301 496 6214.
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 496 6214; fax: +1 301 496 4006.

Received 22 June 2007 ,Revised 16 November 2007 ,Accepted 23 January 2008.

References 

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  3. Curb JD, Abbott RD, Rodriguez BL, Sakkinen P, Popper JS, Yano K, et al. C-reactive protein and the future risk of thromboembolic stroke in healthy men. Circulation. 2003;107:2016–2020
  4. Dik MG, Jonker C, Hack CE, Smit JH, Comijs HC, Eikelenboom P. Serum inflammatory proteins and cognitive decline in older persons. Neurology. 2005;64:1371–1377
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  9. Ridker PM. High-sensitivity C-reactive protein, inflammation, and cardiovascular risk: from concept to clinical practice to clinical benefit. Am. Heart J. 2004;148:S19–S26
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  11. Teng EL, Hasegawa K, Homma A, Imai Y, Larson E, Graves A, et al. The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int. Psychogeriatr. 1994;6:45–58(discussion 62)
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  13. Weuve J, Ridker PM, Cook NR, Buring JE, Grodstein F. High-sensitivity C-reactive protein and cognitive function in older women. Epidemiology. 2006;17:183–189
  14. White L, Petrovitch H, Ross G, Masaki KH, Abbott RD, Teng EL, et al. Prevalence of dementia in older Japanese-American men in Hawaii: the Honolulu-Asia Aging Study. JAMA. 1996;276:955–960
  15. Yaffe K, Kanaya A, Lindquist K, Simonsick EM, Harris T, Shorr RI, et al. The metabolic syndrome, inflammation, and risk of cognitive decline. JAMA. 2004;292:2237–2242
  16. Yaffe K, Lindquist K, Penninx BW, Simonsick EM, Pahor M, Kritchevsky S, et al. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology. 2003;61:76–80

PII: S0197-4580(08)00030-4

doi: 10.1016/j.neurobiolaging.2008.01.008

Neurobiology of Aging
Volume 30, Issue 11 , Pages 1724-1727 , November 2009

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