Neurobiology of Aging
Volume 30, Issue 8 , Pages 1238-1244, August 2009

Amyloid precursor protein increases cortical neuron size in transgenic mice

  • Esther S. Oh

      Affiliations

    • Department of Medicine, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
    • Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
  • ,
  • Alena V. Savonenko

      Affiliations

    • Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
  • ,
  • Julie F. King

      Affiliations

    • Department of Medicine, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
  • ,
  • Stina M. Fangmark Tucker

      Affiliations

    • Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
  • ,
  • Gay L. Rudow

      Affiliations

    • Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
  • ,
  • Guilian Xu

      Affiliations

    • Department of Neuroscience, University of Florida, 100 Newell Drive, Gainesville, FL 32610, USA
  • ,
  • David R. Borchelt

      Affiliations

    • Department of Neuroscience, University of Florida, 100 Newell Drive, Gainesville, FL 32610, USA
  • ,
  • Juan C. Troncoso

      Affiliations

    • Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
    • Department of Neurology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
    • Corresponding Author InformationCorresponding author at: Department of Pathology, The Johns Hopkins University School of Medicine, 558 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA. Tel.: +410 955 5165; fax: +410 955 9777.

Received 18 October 2007; received in revised form 13 December 2007; accepted 28 December 2007. published online 28 February 2008.

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 All procedures were conducted according to NIH guide for animal care and approved by the JHU Institutional Animal Care and Use Committee.

PII: S0197-4580(08)00003-1

doi:10.1016/j.neurobiolaging.2007.12.024

Neurobiology of Aging
Volume 30, Issue 8 , Pages 1238-1244, August 2009