Neurobiology of Aging
Volume 30, Issue 11 , Pages 1777-1791 , November 2009

Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice

  • Alexandra Bernardo

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
  • ,
  • Fiona E. Harrison

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
  • ,
  • Meghan McCord

      Affiliations

    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
  • ,
  • Jiali Zhao

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
  • ,
  • Aleksandra Bruchey

      Affiliations

    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
  • ,
  • Sean S. Davies

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
  • ,
  • L. Jackson Roberts II

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
  • ,
  • Paul M. Mathews

      Affiliations

    • Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Department of Psychiatry, New York University Medical Center, Orangeburg, NY, United States
  • ,
  • Yasuji Matsuoka

      Affiliations

    • Department of Neurology, Georgetown University, Washington, DC, United States
  • ,
  • Toshio Ariga

      Affiliations

    • Institute of Molecular Medicine and Genetics and Institute of Neuroscience, Medical College of Georgia, Augusta, GA, United States
  • ,
  • Robert K. Yu

      Affiliations

    • Institute of Molecular Medicine and Genetics and Institute of Neuroscience, Medical College of Georgia, Augusta, GA, United States
  • ,
  • Rebecca Thompson

      Affiliations

    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
  • ,
  • Michael P. McDonald

      Affiliations

    • Department of Pharmacology, Vanderbilt University, Nashville, TN, United States
    • Program in Neuroscience, Vanderbilt University, Nashville, TN, United States
    • Departments of Neurology and Anatomy & Neurobiology, University of Tennessee Health Science Center, Memphis, TN, United States
    • Corresponding Author InformationCorresponding author at: University of Tennessee Health Science Center, 855 Monroe Avenue, Link Building, Room 415, Memphis, TN 38163, United States. Tel.: +1 901 448 4648.

Received 11 October 2007 ,Revised 21 December 2007 ,Accepted 21 December 2007.

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PII: S0197-4580(07)00498-8

doi: 10.1016/j.neurobiolaging.2007.12.022

Neurobiology of Aging
Volume 30, Issue 11 , Pages 1777-1791 , November 2009