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Neurobiology of Aging
Volume 30, Issue 10
, Pages 1614-1625
, October 2009
Septal grafts restore cognitive abilities and amyloid precursor protein metabolism
References
- . Secretion kinetics of Alzheimer's amyloid beta-protein differs from secreted beta-amyloid precursor protein. Biochem. Biophys. Res. Commun. 1995;214:490–495
- . Increased beta-amyloid precursor protein mRNA in the rat cerebral cortex and hippocampus after chronic systemic atropine treatment. Neurosci. Lett. 1996;210:13–16
- . Age and damage induced changes in amyloid protein precursor immunohistochemistry in the rat brain. J. Comp. Neurol. 1994;342:69–77
- . Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. J. Neurosci. 1994;14:4507–4519
- . Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation. Acta Physiol. Scand. Suppl. 1983;522:1–7
- . Neural transplantation in adult rats. In: Dunnett SB, Björklund A editor. Neural Transplantation. A Practical Approach. Oxford: Oxford University Press; 1992;p. 57–78
- . Selective antibody-induced cholinergic cell and synapse loss produce sustained hippocampal and cortical hypometabolism with correlated cognitive deficits. Exp. Neurol. 2001;170:36–47
- . Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice. PNAS. 2000;97:6826–6831
- . Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 1995;65:1431–1444
- . Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells. PNAS. 1996;93:8046–8050
- . Cleavage of amyloid beta peptide during constitutive processing of its precursor. Science. 1990;248:1122–1124
- . Regulated secretion of beta-amyloid precursor protein in rat brain. J. Neurosci. 1995;15:7442–7451
- . Differential effects of amyloid peptides beta-(1–40) and beta-(25–35) injections into the rat nucleus basalis. Neuroscience. 1995;66:781–792
- . Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature. 1992;359:322–325
- . Alzheimer's disease: the amyloid cascade hypothesis. Science. 1992;256:184–185
- . The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297:353–356
- . Cholinotoxic effects of beta-amyloid (1–42) peptide on cortical projections of the rat nucleus basalis magnocellularis. Brain Res. 1995;695:71–75
- . Beta-amyloid (1–42) affects cholinergic but not parvalbumin-containing neurons in the septal complex of the rat. Brain Res. 1995;698:270–274
- . Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor. J. Neurosci. 1994;14:1271–1289
- . A modified histochemical technique to visualize acetylcholinesterase-containing axons. J. Histochem. Cytochem. 1985;33:134–140
- . Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors. Eur. J. Pharmacol. 2000;393:255–263
- . Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science. 1996;274:99–102
- . The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 1987;325:733–736
- . Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices. J. Neurosci. 1996;16:1034–1040
- . Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. J. Psychiat. Neurosci. 2004;29:427–441
- . Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices. Neurochem. Int. 1997;30:557–563
- . Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth. PNAS. 1993;90:4748–4752
- . Functional activity of intrahippocampal septal grafts is regulated by catecholaminergic host afferents as studied by microdialysis of acetylcholine. Brain Res. 1993;618:47–56
- . Selective lesioning of the basal forebrain cholinergic system by intraventricular 192 IgG-saporin: behavioural, biochemical and stereological studies in the rat. Eur. J. Neurosci. 1995;7:329–343
- . Chronic elevation of amyloid precursor protein expression in the neocortex and hippocampus of rats with selective cholinergic lesions. Neurosci. Lett. 1998;257:53–56
- . Amelioration of spatial navigation and short-term memory deficits by grafts of foetal basal forebrain tissue placed into the hippocampus and cortex of rats with selective cholinergic lesions. Eur. J. Neurosci. 1998;10:2353–2370
- . Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. PNAS. 1995;92:8083–8087
- . Chronic cognitive deficits and amyloid precursor protein elevation after selective immunotoxin lesions of the basal forebrain cholinergic system. Neuroreport. 1998;9:547–552
- . Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation. PNAS. 1999;96:12108–12113
- . Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction. Brain Res. 1996;706:181–193
- . Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. PNAS. 1998;95:12683–12688
- . Regulation of amyloid precursor protein cleavage. J. Neurochem. 1999;72:443–460
- . The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron. 1992;9:129–137
- Moran, P.M., Higgins, L.S., Cordell, B., Moser, P.C., 1995. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human ß-amyloid precursor protein. PNAS 92, 5341–5345.
- . Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. Neuroreport. 1995;6:633–666
- . Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods. 1984;11:47–60
- . Muscarinic M1 receptor agonists increase the secretion of the amyloid precursor protein ectodomain. Life Sci. 1997;60:985–991
- . The Alzheimer amyloid precursor-related transcript lacking the beta/A4 sequence is specifically increased in Alzheimer's disease brain. Neuron. 1990;5:329–338
- . Alzheimer's disease: a re-examination of the amyloid hypothesis. Trends Neurosci. 1998;21:15–19
- . Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science. 1992;258:304–307
- . Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices. PNAS. 1993;90:5191–5193
- . The Rat Brain in Stereotaxic Coordinates. 2nd Edition. Academic Press; 1986;
- . Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain. PNAS. 1996;93:8068–8071
- . Muscarinic control of amyloid precursor protein secretion in rat cerebral cortex and cerebellum. Brain Res. 1996;742:299–304
- . Lesion of septal-hippocampal neurons with 192 IgG-saporin alters function of M1 muscarinic receptors. Neuropharmacology. 1999;38:579–586
- . Short- and long-term effect of acetylcholinesterase inhibition on the expression and metabolism of the amyloid precursor protein. Mol. Psychiatry. 2001;6:520–528
- . NIH Image: a public domain image processing program for the Macintosh. Microbeam Anal. Soc. J. 1995;4:37–149
- . Cholinergic activity and amyloid precursor protein metabolism. Brain Res. Rev. 1997;25:50–69
- . Basal forebrain grafts in the rat neocortex restore in vivo acetylcholine release and respond to behavioural activation. Neuroscience. 1993;55:353–362
- . In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity. Eur. J. Neurosci. 1997;9:2125–2134
- . The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling. Prog. Neurobiol. 1998;56:541–569
- . Basal forebrain cholinergic dysfunction in Alzheimer's disease-interrelationship with beta-amyloid, inflammation and neurotrophin signaling. Neurochem. Res. 2005;30:895–908
- . Septal transplants ameliorate spatial deficits and restore cholinergic functions in rats with a damaged septo-hippocampal connection.. Brain Res. 1989;500:139–148
- . Alzheimer's disease: genotypes, phenotypes, and treatments. Science. 1997;275:630–631
- . Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu. Rev. Pharmacol. Toxicol. 2003;43:545–584
- . Effects of nicotine on APP secretion and Abeta- or CT(105)-induced toxicity. Biol. Psychiatry. 2001;49:240–247
- . Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice. Exp. Neurol. 2005;193:469–480
- . Production of the Alzheimer amyloid beta protein by normal proteolytic processing. Science. 1992;258:126–129
- . Intrahippocampal transplants of septal cholinergic neurons: choline acetyltransferase activity, muscarinic receptor binding, and spatial memory function. Brain Res. 1993;632:41–47
- . 192 immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells. Neuroscience. 1995;65:463–476
- . Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation. PNAS. 1993;90:8712–8716
- . Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats. J. Neurosci. 1995;15:4896–4905
- . Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 1991;231:482–497
- . Immunolesioning: selective destruction of neurons using immunotoxin to rat NGF receptor.. Brain Res. 1991;562:149–153
- . Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures. Neuroscience. 2002;115:201–211
PII: S0197-4580(07)00491-5
doi: 10.1016/j.neurobiolaging.2007.12.018
© 2007 Elsevier Inc. All rights reserved.
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Neurobiology of Aging
Volume 30, Issue 10
, Pages 1614-1625
, October 2009
