Neurobiology of Aging
Volume 30, Issue 10 , Pages 1587-1600 , October 2009

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

  • Saravanan S. Karuppagounder

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • Hui Xu

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • Qingli Shi

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • Lian H. Chen

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • Steve Pedrini

      Affiliations

    • Thomas Jefferson University, Farber Institute for the Neurosciences, 900 Walnut Street, Suite 467, Philadelphia, PA 19107, United States
    • ,
  • David Pechman

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • Harriet Baker

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • ,
  • M. Flint Beal

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, 525E, 68th Street, New York, NY 10021, United States
    • ,
  • Sam E. Gandy

      Affiliations

    • Thomas Jefferson University, Farber Institute for the Neurosciences, 900 Walnut Street, Suite 467, Philadelphia, PA 19107, United States
    • ,
  • Gary E. Gibson

      Affiliations

    • Department of Neurology and Neurosciences, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 914 597 2291; fax: +1 914 597 2757.

Received 24 May 2007 ,Revised 11 December 2007 ,Accepted 14 December 2007.

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PII: S0197-4580(07)00488-5

doi: 10.1016/j.neurobiolaging.2007.12.013

Neurobiology of Aging
Volume 30, Issue 10 , Pages 1587-1600 , October 2009

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