Neurobiology of Aging
Volume 30, Issue 7 , Pages 1091-1098 , July 2009

Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP

  • Liang Li

      Affiliations

    • Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • ,
  • Xiaojie Zhang

      Affiliations

    • Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • ,
  • Dehua Yang

      Affiliations

    • Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • ,
  • Guangrui Luo

      Affiliations

    • Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • ,
  • Shen Chen

      Affiliations

    • Institute of Neurology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • ,
  • Weidong Le

      Affiliations

    • Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • Institute of Neurology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, PR China
    • Corresponding Author InformationCorresponding author at: Institute of Neurology, Ruijin Hospital, Jiao Tong University School of Medicine, Shanghai 200025, PR China. Tel.: +86 21 54669084; fax: +86 21 54669084.

Received 1 July 2007 ,Revised 1 October 2007 ,Accepted 15 October 2007.

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PII: S0197-4580(07)00410-1

doi: 10.1016/j.neurobiolaging.2007.10.011

Neurobiology of Aging
Volume 30, Issue 7 , Pages 1091-1098 , July 2009

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