« Previous
Next »
Neurobiology of Aging
Volume 30, Issue 7
, Pages 1011-1025
, July 2009
Neurodegeneration and peroxidases
References
- . Plasma lipid peroxidation in sporadic Parkinson's disease. Role of the l-dopa. J. Neurol. Sci. 2006;240:31–36
- . Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NkκB-dependent mechanism. Proc. Natl. Acad. Sci. U.S.A. 1998;95:5795–5800
- . Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc. Natl. Acad. Sci. U.S.A. 2006;103:9685–9690
- . Redox properties of the couple compound I/native enzyme of myeloperoxidase and eosinophil peroxidase. Eur. J. Biochem. 2001;268:5124–5148
- . Redox properties of myeloperoxidase. Redox Rep. 2003;8:179–186
- . Heme binding to amyloid-beta peptide: mechanistic role in Alzheimer's disease. J. Alzheimers Dis. 2006;10:255–266
- . Amyloid-β peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 2006;103:3381–3386
- . Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice. J. Neurochem. 1998;71:1635–1642
- . Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res. Brain Res. Rev. 1997;25:335–358
- . Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): seven cases. Neurology. 1985;35:949–956
- . Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure. Glia. 2004;46:402–409
- . Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification. J. Neurosci. Res. 1991;29:336–345
- . Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity. Brain Res. 2006;1069:198–206
- . Time course and site(s) of cytochrome c tyrosine nitration by peroxynitrite. Biochemistry. 2005;44:8038–8046
- . The proteasomal inhibition model of Parkinson's disease: “Boon or bust”?. Ann. Neurol. 2006;60:158–161
- . Mitochondria take center stage in aging and neurodegeneration. Ann. Neurol. 2005;58:495–505
- . Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans. 1993;21:330–334
- . Peroxidase activity and, structural transitions of cytochrome c bound to cardiolipin-containing membranes. Biochemistry. 2006;45:4998–5009
- . The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons. J. Neurochem. 1991;56:1441–1444
- . Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases. Neurobiol. Dis. 2005;22:25–32
- . Clinical potential of minocycline for neurodegenerative disorders. Neurobiol. Dis. 2004;17:359–366
- . Early release and subsequent caspase-mediated degradation of cytochrome c in apoptotic cerebellar granule cells. FEBS Lett. 1999;457:126–130
- . Elevated “hydroxyl radical” generation in vivo in an animal model of amyotrophic lateral sclerosis. J. Neurochem. 1998;71:1321–1324
- . Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide. J. Biol. Chem. 1999;274:10806–19802
- . Albumin oxidation to diverse radicals by the peroxidase activity of Cu-Zn-superoxide dismutase in the presence of bicarbonate or nitrite: diffusible radicals produce cysteinyl and solvent-exposed and -unexposed tyrosyl radicals. Biochemistry. 2004;43:344–351
- . Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 2004;27:723–749
- . Activation of cytochrome c to a peroxidase compound I-type intermediate by H2O2: relevance to redox signalling in apoptosis. Biochem. Soc. Symp. 2004;71:97–106
- . The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). New Engl. J. Med. 1985;312:1418–1421
- . Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis. J. Biol. Chem. 2005;280:16295–16304
- . Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J. 2005;19:2040–2041
- . Cytochrome c nitration by peroxynitrite. J. Biol. Chem. 2000;275:21409–21415
- . Cytochrome c: a catalyst and target of nitrite-hydrogen peroxide-dependent protein nitration. Arch. Biochem. Biophys. 2004;421:99–107
- . Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J. Biol. Chem. 2004;279:13256–13264
- . Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases. J. Biol. Chem. 2005;280:11648–11655
- . Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice. J. Neurosci. 2005;25:6594–6600
- . Continuous subcutaneous waking day apomorphine in the long term treatment of levodopa induced interdose dyskinesias in Parkinson's disease. J. Neurol. Neurosurg. Psychiatry. 1998;64:573–576
- . Lack of oestrogen protection in amyloid-mediated endothelial damage due to protein nitrotyrosination. Brain. 2005;128:1613–1621
- . Antitumor activity of an immobilized peroxidase system against murine Ehrlich ascites is mediated by the immune system. Proc. Soc. Exp. Biol. Med. 1993;204:306–311
- . Chronic parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Res. 1979;1:249–254
- . Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis. Brain Res. 1990;519:266–276
- . Diffusion of peroxynitrite across erythrocyte membranes. Proc. Natl. Acad. Sci. U.S.A. 1998;95:3566–3571
- . Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. Ann. Neurol. 2002;52:771–778
- . Variability and functional recovery in the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of parkinsonism in monkeys. Neuroscience. 1986;18:817–822
- . The structure of heme proteins Compounds I and II: some misconceptions. Free Radic. Biol. Med. 1998;24:1338–1346
- . The cytotoxic activity of lactoperoxidase: enhancement and inhibition by neuroactive compounds. Free Radic. Biol. Med. 2004;37:839–849
- . Role of peroxidases in Parkinson's disease: a hypothesis. Free Radic. Biol. Med. 2005;38:1296–1310
- . Immobilized enzymes in biochemical analysis. In: Glick D editors. Methods of Biochemical Analysis. vol. 25:New York: John Wiley and Sons; 1979;p. 136–201
- . Peroxidative activities of hemoglobin and hemoglobin derivatives. In: Everse J, Vandegriff KD, Winslow RM editor. Hemoglobins; Biochemical and Analytical Methods (Methods in Enzymology). vol. 231:San Diego: Academic Press; 1994;p. 547–561
- . Antitumour activity of peroxidases. Br. J. Cancer. 1985;51:743–746
- . Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation. Glia. 2006;53:233–240
- . Micochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease. Ann. N Y Acad. Sci. 2003;991:111–119
- . Similarities and differences between MPTP-induced parkinsonism and Parkinson's disease. Neuropathologic considerations. Adv. Neurol. 1993;60:600–608
- . Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease. FASEB J. 2003;17:1954–1956
- Garcia-Allano, M., Borrelli, L.A., Rozkalne, A., Hyman, B.T., Bacskai, B.J., 2007. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alkzheimer mouse model. J. Neurochem. doi:10.1111/j.1471-4159.2007.04613.x.
- . Experimental brain inflammation and neurodegeneration as model of Alzheimer's disease: protective effects of selective COX-2 inhibitors. Int. J. Immunopathol. Pharmacol. 2003;16(2 Suppl.):31–40
- . Reactivity of peroxynitrite versus simultaneous generation of NO
and O2
− toward NADH. Chem. Res. Toxicol. 2000;13:736–741 - . Evidence of neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 1996;149:21–28
- . Neuronal expression of myeloperoxidase is increased in Alzheimer's disease. J. Neurochem. 2004;90:724–733
- . Neuromelanogenic and cytotoxic properties of canine brainstem peroxidase. J. Neurochem. 1987;48:876–882
- . Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Neurosci. 2001;21:6569–6576
- . Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation. J. Biol. Chem. 1997;272:17086–17090
- . The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies. J. Neurol. Sci. 1997;152:S67–S73
- . MPP+ induces NADH dependent superoxide formation and enhances NADH dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 1990;170:1049–1055
- . Role of cytochrome c as a stimulator of α -synuclein aggregation in Lewy body disease. J. Biol. Chem. 1999;274:28849–28852
- . Molecular mechanisms of neuronal cell death. Ann. N Y Acad. Sci. 2003;991:237–250
- . Eosinophil peroxidase: occurrence and biological function. In: Everse J, Everse KE, Grisham MB editor. Peroxidases in Chemistry and Biology. vol. 1:Boca Raton: CRC Press; 1991;p. 105–121
- . The role of glial reaction and inflammation in Parkinson's disease. Ann. N Y Acad. Sci. 2003;991:214–228
- . Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain. Acta Neuropathol. 2001;101:2–8
- . Cyclin D1 and cyclin E are co-localized with cyclooxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. J. Neuropathol. Exp. Neurol. 2002;61:678–688
- . Neuroprotective therapies for Alzheimer's disease. Curr. Pharm. Des. 2006;12:705–717
- . Biochemical properties of cytochrome c nitrated by peroxynitrite. Biochimie. 2006;88:53–58
- . Peroxidation and externalization of phosphatidylserine associated with release of cytochrome c from mitochondria. Free Radic. Biol. Med. 2003;35:814–825
- . Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effect. Life Sci. 1985;36:219–224
- . Formation of high molecular weight complexes of mutant Cu-Zn superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U.S.A. 2000;97:12571–12576
- . Apolipoprotein E is highly susceptible to oxidation by myeloperoxidase, an enzyme present in the brain. Neurosci. Lett. 1996;210:61–64
- . Mitochondrial control of neuron death and its role in neurodegenerative disorders. J. Physiol. Biochem. 2003;59:129–141
- . The “pro-apoptotoc genies” get out of mitochondria: oxidative lipidomics and redox activity of cytochrome c/cardiolipin complexes. Chem. Biol. Interact. 2006;163:15–28
- . Enhanced oxidative damage by the familial amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutants. Biochim. Biophys. Acta. 2000;1524:162–170
- . Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice. J. Neurosci. 2005;25:164–172
- . Myeloperoxidase: occurrence and biological function. In: Everse J, Everse KE, Grisham MB editor. Peroxidases in Chemistry and Biology. vol. 1:Boca Raton: CRC Press; 1991;p. 1–35
- . Neuroprotective effects of creatine in a transgenic animal model of amylotrophic lateral sclerosis. Nat. Med. 1999;5:347–350
- . Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys. Ann. Neurol. 2006;60:264–268
- . Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science. 1997;277:559–562
- . Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiol. Dis. 2002;10:268–278
- . Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 1983;219:979–980
- . Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann. Neurol. 1999;46:598–605
- . Evidence for the role of a peroxidase compound I-type intermediate in the oxidation of glutathione, NADH, ascorbate, and dichlorofluorescin by cytochrome c/H2O2. Implications for oxidative stress during apoptosis. J. Biol. Chem. 2003;278:29410–29419
- . The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death. Curr. Alzheimer Res. 2005;2:389–402
- . Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science. 2000;288:335–339
- . Cyclooxygenase-2 and inflammation in atherosclerosis. Curr. Opin. Pharmacol. 2004;4:116–123
- . Glutathione metabolism during aging and in Alzheimer's disease. Ann. N Y Acad. Sci. 2004;1019:346–349
- . Mechanism of carbon dioxide-catalyzed oxidation of tyrosine by peroxynitrite. Biochemistry. 1996;35:7855–7861
- . Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis. Eur. J. Neurosci. 2003;18:1527–1534
- . Mitochondrial dysfunction and its role in motor neuron degeneration in ALS. Mitochondrion. 2005;5:77–87
- . Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism. Nature. 1984;311:464–467
- . Continuous assay for cytolytic activity. In: Di Sabato G, Everse J editor. Immunochemical Techniques. Part J. Phagocytosis and Cell-Mediated Cytotoxicity (Methods in Enzymology). vol. 132:San Diego: Academic Press; 1986;p. 491–498
- . Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve. 2002;26:459–470
- . NSAIDs and Alzheimer's disease: epidemiological, animal model and clinical studies. Neurobiol. Aging. 2007;28:639–647
- . Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology. 1988;38:1285–1291
- . Inositol stereoisomers stabilize oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta-induced toxicity. J. Biol. Chem. 2000;275:18495–18502
- . Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann. Neurol. 2004;56:149–162
- . Proteasome inhibitor-induced model of Parkinson's disease. Ann. Neurol. 2006;60:243–247
- . Spontaneous regeneration of nigrostriatal dopaminergic neurons in MPTP-treated C57BL/6 mice. Biochem. Biophys. Res. Commun. 1998;248:660–663
- . Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J. Neuropathol. Exp. Neurol. 2004;63:901–910
- . Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links β-amyloid (Aβ) and generates Aβ-COX-2 hetero-oligomers that are increased in Alzheimer's disease. J. Biol. Chem. 2004;279:14673–14678
- . J. Exp. Med. 2005;202:1163–1169
- . Cu/Zn superoxide dismutase-like immunoreactivity is present in Lewy bodies from Parkinson disease: a light and electron microscopic immunocytochemical study. Acta Neuropathol. 1995;89:471–474
- . Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease. J. Biol. Chem. 1999;274:34621–34628
- . Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc. Natl. Acad. Sci. U.S.A. 2005;102:19126–19131
- . Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice—a model of familial amyotrophic lateral sclerosis. Free Radic. Biol. Med. 2005;38:960–968
- . Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice—a model of familial Parkinson's disease. Neurobiol. Dis. 2005;18:492–498
- . Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice—a model of amyotrophic lateral sclerosis. Free Radic. Biol. Med. 2005;39:453–462
- . Inhibition of cyclooxygenase as potential novel therapeutic strategy in N1411 presenilin-2 familial Alzheimer's disease. Mol. Psychiatry. 2006;11:172–181
- . Nitric oxide, oxidants, and protein tyrosine nitration. Proc. Natl. Acad. Sci. U.S.A. 2004;101:4003–4008
- . Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease. Biochemistry. 2005;44:1690–1700
- . Cyclooxygenase-2: from inflammation to carcinogenesis. Novartis Found Symp. 2004;256:215–221
- . Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch. Neurol. 2003;60:1685–1991
- . Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis. Glia. 2005;51:241–253
- . Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition. Neuropathol. Appl. Neurobiol. 2005;31:467–485
- . Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions. J. Biol. Chem. 2004;279:10710–10719
- . The role of metals in neurodegenerative diseases. Cell Mol. Biol. 2000;46:731–741
- . Non-steroidal anti-inflammatory drugs protect against Parkinson neurodegeneration. Arch. Neurol. 2003;60:1043–1044
- . NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?. Trends Biochem. Sci. 2003;28:646–654
- . The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases. Mol. Cell Biochem. 1997;174:193–197
- . Lewy bodies. Proc. Natl. Acad. Sci. U.S.A. 2006;103:1661–1668
- . Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 1994;36:348–355
- . Cyclooxygenase isoenzymes: the biology of prostaglandin synthesis and inhibition. Pharmacol. Rev. 2004;56:387–437
- . Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 1997;17:2653–2657
- . Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide. Biochemistry. 2007;46:2881–2891
- . The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. Eur. J. Pharmacol. 1986;129:339–345
- . Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice. Brain Res. 1997;749:44–52
- . Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases. Brain Res. Bull. 2001;55:175–185
- . The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?. J. Neuropathol. Exp. Neurol. 2005;64:649–664
- . Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis. Free Radic. Biol. Med. 2003;35:45–58
- . Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease. Synapse. 2001;39:167–174
- . Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 2003;100:5473–5478
- . COX-2 and neurodegeneration in Parkinson's disease. Ann. N Y Acad. Sci. 2003;991:272–277
- . Nitric oxide and reactive oxygen species in Parkinson's disease. IUBMB Life. 2003;55:329–335
- . A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 2000;267:22–25
- . Suicide inactivation of peroxidases and the challenge of engineering more robust enzymes. Chem. Biol. 2002;9:555–565
- . Minocyclin delaysdisease onset and mortality in a transgenic mouse model of ALS. Neuroreport. 2002;13:1067–1070
- . Nitric oxide inhibits peroxidase activity of cytochrome c.cardiolipin complex and blocks cardiolipin oxidation. J. Biol. Chem. 2006;281:14554–14562
- . MPP+-induced COX-2 activation and subsquent dopaminergic neurodegeneration. FASEB J. 2005;19:1134–1136
- . Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease. J. Neuropathol. Exp. Neurol. 2006;65:142–151
- . Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science. 1996;271:515–518
- . The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease. Neuroinflammation. 2006;3:30
- . Cytoplasmic cytochrome c immunolabelling in dystrophic neurites in Alzheimer's disease. Acta Neuropathol. 2006;112:429–437
- . Effect of MAO-B inhibitors on MPP+ toxicity in vivo. Ann. N Y Acad. Sci. 2000;899:255–261
- . Mitochondrial degeneration in amyotrophic lateral sclerosis. J. Bioenerg. Biomembr. 2004;36:395–399
- . A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: an enhancement of free radical formation due to a decrease in Km for hydrogen peroxide. Proc. Natl. Acad. Sci. 1996;93:5709–5714
- . A familial amyotrophic lateral sclerosis-associated A4
V Cu,Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value. J. Biol. Chem. 1997;272:8861–8863 - . Enhanced free radical generation of FALS-associated Cu,Zn-SOD mutants. Neurotox. Res. 1999;1:91–97
- . The pivotal role of iron in NF-κB activation and nigrostriatal dopaminergic neurodegeneration. Ann. N Y Acad. Sci. 1999;890:7–25
- . Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics. J. Biol. Chem. 2002;277:1013–1020
- . Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products. J. Biol. Chem. 2003;278:24078–24089
- . Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J. 2005;19:533–542
- . Microglial activation induced by neurodegeneration: a proteomic analysis. Mol. Cell Proteomics. 2005;4:1471–1479
- . Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 2002;417:74–78
- . Mitochondrial failures in Alzheimer's disease. Am. J. Alzheimers Dis. Other Dem. 2004;19:345–352
- . Presenilin mutation: a deadly first hit in Alzheimer disease. Free Radic. Biol. Med. 2006;40:737–739
- . Production of nitrite by neonatal rat microglial cells/brain macrophages. Cell Immunol. 1992;141:111–120
- . Acetaldehyde directly enhances MPP+ neurotoxicity and delays its elimination from the striatum. Brain Res. 1989;501:11–22
PII: S0197-4580(07)00409-5
doi: 10.1016/j.neurobiolaging.2007.10.007
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 30, Issue 7
, Pages 1011-1025
, July 2009
