Neurobiology of Aging
Volume 30, Issue 5 , Pages 769-781, May 2009

Genetic priming of a proinflammatory profile predicts low IQ in octogenarians

  • K.S. Krabbe

      Affiliations

    • The Centre of Inflammation and Metabolism, Department of Infectious Diseases and CMRC, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author at: Centre of Inflammation and Metabolism, Rigshospitalet, Section 7641, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. Tel.: +45 35 45 73 77; fax: +45 35 45 76 44.
  • ,
  • E.L. Mortensen

      Affiliations

    • Institute of Public Health, University of Copenhagen, Denmark
    • Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
    • Present address: Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Øster Farimagsgade 5, opg Z, 1 sal, DK-1014 Copenhagen, Denmark.
  • ,
  • K. Avlund

      Affiliations

    • Institute of Public Health, University of Copenhagen, Denmark
    • Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
    • Present address: Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Øster Farimagsgade 5, Building 9, Post Box 2099, DK-1014 Copenhagen, Denmark.
  • ,
  • H. Pilegaard

      Affiliations

    • The August Krogh Building, Institute of Molecular Biology, University of Copenhagen, Denmark
    • Present address: The August Krogh Building, Room 431, Institute of Molecular Biology, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen, Denmark.
  • ,
  • L. Christiansen

      Affiliations

    • Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Denmark
    • Present address: Institute of Public Health, Department of Epidemiology, University of Southern Denmark, J.B. Winsløws Vej 9, DK-5000 Odense C, Denmark.
  • ,
  • A.N. Pedersen

      Affiliations

    • National Food Institute, Technical University of Denmark, Denmark
    • Present address: National Food Institute, Technical University of Denmark, Anker Engelundsvej 1, 101 A, DK-2800 Kgs. Lyngby, Denmark.
  • ,
  • M. Schroll

      Affiliations

    • Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
    • Present address: Research Centre for Prevention and Health, Building 84/85, Glostrup University Hospital, DK-2600 Glostrup, Denmark.
  • ,
  • T. Jørgensen

      Affiliations

    • Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
    • Present address: Research Centre for Prevention and Health, Building 84/85, Glostrup University Hospital, DK-2600 Glostrup, Denmark.
  • ,
  • B.K. Pedersen

      Affiliations

    • The Centre of Inflammation and Metabolism, Department of Infectious Diseases and CMRC, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    • Present address: Centre of Inflammation and Metabolism, Rigshospitalet, Section 7641, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
  • ,
  • H. Bruunsgaard

      Affiliations

    • The Centre of Inflammation and Metabolism, Department of Infectious Diseases and CMRC, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    • Present address: Centre of Inflammation and Metabolism, Rigshospitalet, Section 7641, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

Received 8 May 2007; received in revised form 11 July 2007; accepted 21 August 2007. published online 04 October 2007.

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PII: S0197-4580(07)00347-8

doi:10.1016/j.neurobiolaging.2007.08.013

Neurobiology of Aging
Volume 30, Issue 5 , Pages 769-781, May 2009