« Previous
Next »
Neurobiology of Aging
Volume 30, Issue 4
, Pages 561-573
, April 2009
Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia
References
- . Controlling the false discovery rate—a practical and powerful approach to multiple testing. J. R. Soc. Ser. B: Methodol. 1995;57:289–300
- . Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation. Ageing Res. Rev. 2005;4:481–512
- . Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc. Natl. Acad. Sci. U.S.A. 2004;101:2173–2178
- . The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br. J. Psychiatry. 1968;114:797–811
- . A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics. 2003;19:185–193
- . Staging of Alzheimer disease-associated neurofibrillarypathology using paraffin sections and immunocytochemistry. Acta Neuropathol. 2006;112:389–404
- . Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.). 1991;82:239–259
- . Staging of Alzheimer-related cortical destruction. Int. Psychogeriatr. 1997;9(Suppl. 1):257–261
- . Vulnerability of select neuronal types to Alzheimer's disease. Ann. N.Y. Acad. Sci. 2002;924:53–61
- . Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease. Neuroscience. 2003;117:577–592
- . Cholinergic markers in elderly patients with early signs of Alzheimer disease. JAMA. 1999;281:1401–1406
- . Cholinergic markers are not decreased in early Alzheimer's disease. JAMA. 1999;281:1401–1406
- . Neuropeptide abnormalities in patients with early Alzheimer disease. Arch. Gen. Psychiatry. 1999;56:981–987
- . The Clinical Dementia Rating scale: community-based validation of “profound’ and “terminal’ stages. Neurology. 1996;46:1746–1749
- . Alzheimer's disease: mRNA expression profiles of multiple patients show alterations of genes involved with calcium signaling. Neurobiol. Dis. 2006;21:618–625
- . Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology. 2003;60:1495–1500
- . Single cell gene expression profiling in Alzheimer's disease. NeuroRx. 2006;3:302–318
- . Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Neurochem. Res. 2004;29:1053–1064
- . Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann. Neurol. 2000;48:77–87
- . A hundred years of Alzheimer's disease research. Neuron. 2006;52:3–13
- . Tau protein abnormalities associated with the progression of Alzheimer disease type dementia. Neurobiol. Aging. 2006;28:1–7
- . Pathophysiology of dementia. In: Tasman A, Kay J, Lieberman J editor. Psychiatry. vol. 1:Chichester, England: John Wiley & Sons; 2003;p. 338–349
- . Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Arch. Neurol. 1998;55:1185–1191
- . Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease. Arch. Neurol. 1999;56:713–718
- . Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4:249–264
- . Variations in differential gene expression patterns across multiple brain regions in schizophrenia. Schizo. Res. 2005;77:241–252
- . Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions: a gene ontology study. Schizo. Res. 2005;79:157–173
- . Large-scale microarray studies of gene expression in multiple regions of the brain in schizophrenia and Alzheimer's disease. Int. Rev. Neurobiol. 2005;63:41–82
- . Diagnosis of Alzheimer's disease. Arch. Neurol. 1985;42:1097–1105
- . A gene expression profile of Alzheimer's disease. DNA Cell Biol. 2001;20:683–695
- . The synaptic organization of the neocortex in Alzheimer's disease. Med. Hypotheses. 1993;41:334–340
- . The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991;41:479–486
- . The clinical dementia rating (CDR): current version and scoring rules. Neurology. 1993;43:2412–2414
- . Mild cognitive impairment represents early-stage Alzheimer disease. Arch. Neurol. 2001;58:397–405
- . Neuropathology of normal aging in cerebral cortex. In: Beal MF, Lang AE, Ludolph A editor. Neurodegenerative Diseases. Cambridge: Cambridge University Press; 2005;p. 396–406
- . Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA. 2000;283:1571–1577
- . Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol. Aging. 2006;[Epub ahead of print]
- . Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline. Arch. Neurol. 2001;58:2025–2032
- . Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia. J. Neurosci. Res. 2001;65:471–476
- . Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch. Neurol. 2001;58:1395–1402
- . Tangles and plaques in nondemented aging and “preclinical” Alzheimer's disease. Ann. Neurol. 1999;45:358–368
- . The relationship of neuropsychological performance to functional status in old age: a comparison of nursing home residents and community dwellers. Am. J. Geriatr. Psychiatry. 2005;13:450–459
- . Microarray analysis in Alzheimer's disease and normal aging. IUBMB Life. 2004;56:349–354
- . 100 years and counting: prospects for defeating Alzheimer's disease. Science. 2006;314:781–784
- . Application of a growth curve approach to modeling the progression of Alzheimer's disease. J. Gerontol A: Biol. Sci. Med. Sci. 1996;51:M179–M184
- . Alzheimer's disease and the aging brain. J. Geriatr. Psychiatry Neurol. 2006;19:125–128
- . Observations on the brains of demented old people. J. Neurol. Sci. 1970;11:205–242
- . Formation of diffuse and fibrillar tangles in aging and early Alzheimer's disease. Neurobiol. Aging. 2000;21:1–10
- . Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field. Exp. Neurol. 2005;193:198–206
- . Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Neurobiol. Dis. 2006;21:256–275
- . Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease. Neurobiol. Dis. 2003;12:97–109
☆ Although we are unable at this time to publish the entire array data set, we are committed to sharing the gene expression data broadly with our academic colleagues. We will be happy to collaborate with interested investigators and to interrogate the data set for the expression levels of genes of interest.
PII: S0197-4580(07)00296-5
doi: 10.1016/j.neurobiolaging.2007.07.021
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 30, Issue 4
, Pages 561-573
, April 2009
