« Previous
Next »
Neurobiology of Aging
Volume 29, Issue 7
, Pages 1040-1051
, July 2008
mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys
References
- . NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin. Neuropharmacology. 2005;49(Suppl. 1):135–145
- . Characterization of MK-801-induced behavior as a putative rat model of psychosis. J. Pharmacol. Exp. Ther. 1999;290:1393–1408
- . Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals. Neuron. 2004;42:653–663
- . Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. J. Neurosci. 2004;24:828–835
- . Chronic treatment with small doses of cabergoline prevents dopa-induced dyskinesias in parkinsonian monkeys. Mov. Disord. 2003;18:1436–1441
- . Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys. J. Pharmacol. Exp. Ther. 1995;272:854–859
- . Differing effects of N-methyl-d-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys. J. Pharmacol. Exp. Ther. 1999;290:1034–1040
- . Modulation of levodopa-induced motor response complications by NMDA antagonists in Parkinson's disease. Neurosci. Biobehav. Rev. 1997;21:447–453
- . Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats. J. Neurosci. 2003;23:8302–8309
- . Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism. J. Neurosci. 2002;22:5669–5678
- . Electrophysiology of dopamine in normal and denervated striatal neurons. Trends Neurosci. 2000;23:S57–S63
- . Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias. J. Neuropathol. Exp. Neurol. 2002;61:186–196
- . Dopamine-receptor stimulation: biobehavioral and biochemical consequences. Trends Neurosci. 2000;23:S92–S100
- . Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2002;26:127–138
- . Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease. Neurobiol. Dis. 2003;14:404–416
- . Dopaminergic modulation of NMDA-induced whole cell currents in neostriatal neurons in slices: contribution of calcium conductances. J. Neurophysiol. 1998;79:82–94
- . Striatal mechanisms and pathogenesis of parkinsonian signs and motor complications. Ann. Neurol. 2000;47:S122–S129
- . Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease. Brain Res. Bull. 2006;69:318–326
- . Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats. Eur. J. Pharmacol. 2003;462:73–81
- . Metabotropic glutamate receptors. Cell Tissue Res. 2006;326:483–504
- . Behavioural disorders induced by external globus pallidus dysfunction in primates. II. Anatomical study. Brain. 2004;127:2055–2070
- . D1 dopamine receptor supersensitivity in the dopamine-depleted striatum animal model of Parkinson's disease. Neuroscientist. 2003;9:455–462
- . Neurotensin receptors and dopamine transporters: effects of MPTP lesioning and chronic dopaminergic treatments in monkeys. Synapse. 1999;32:153–164
- . Behavioural disorders induced by external globus pallidus dysfunction in primates. I. Behavioural study. Brain. 2004;127:2039–2054
- . Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning. Eur. J. Neurosci. 2005;22:283–287
- . Effect of a selective glutamate antagonist on l-dopa-induced dyskinesias in drug-naive parkinsonian monkeys. Neurobiol. Dis. 2004;15:171–176
- . Dopamine replacement therapy does not restore the full spectrum of normal pallidal activity in the 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine primate model of parkinsonism. J. Neurosci. 2006;26:8101–8114
- . Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey Substantia nigra. J. Neurosci. 2001;21:1838–1847
- . Balance of monosynaptic excitatory and disynaptic inhibitory responses of the globus pallidus induced after stimulation of the subthalamic nucleus in the monkey. J. Neurosci. 2005;25:8611–8619
- . Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia. Neurobiol. Dis. 2004;17:219–236
- . The changing landscape of ischaemic brain injury mechanisms. Nature. 1999;399:A7–A14
- . The N-methyl-d-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications. Pharmacol. Ther. 2003;97:55–85
- . Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 1997;17:5196–5205
- . Localization and physiological roles of metabotropic glutamate receptors in the direct and indirect pathways of the basal ganglia. Amino Acids. 2002;23:185–191
- . Modulation of the basal ganglia by metabotropic glutamate receptors: potential for novel therapeutics. Curr. Drug Targets. CNS. Neurol. Disord. 2002;1:239–250
- . The ‘magic’ of l-dopa: why is it the gold standard Parkinson's disease therapy?. Trends Pharmacol. Sci. 2005;26:341–344
- . Pathophysiology of motor response complications in Parkinson's disease: hypotheses on the why, where, and what. Mov. Disord. 2000;15:3–8
- . Prevention of levodopa-induced dyskinesias by a selective NR1A/2B N-methyl-d-aspartate receptor antagonist in parkinsonian monkeys: implication of preproenkephalin. Mov. Disord. 2006;21:9–17
- . Excitatory cortical inputs to pallidal neurons via the subthalamic nucleus in the monkey. J. Neurophysiol. 2000;84:289–300
- . A common signaling pathway for striatal NMDA and adenosine A2a receptors: implications for the treatment of Parkinson's disease. J. Neurosci. 2000;20:7782–7789
- . NR2B selective NMDA receptor antagonists. Curr. Pharm. Des. 2002;8:845–855
- . Continuous dopamine-receptor stimulation in advanced Parkinson's disease. Trends Neurosci. 2000;23:S109–S115
- . MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. Neuropharmacology. 2005;49:447–455
- . Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism. Eur. J. Neurosci. 2005;22:2765–2774
- . Levodopa-induced dyskinesias improved by a glutamate antagonist in parkinsonian monkeys. Ann. Neurol. 1996;39:574–578
- . Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res. Brain Res. Rev. 1995;20:91–127
- . Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data. Neuropharmacology. 1999;38:735–767
- . In vitro characterization of [3H]MethoxyPyEP, an mGluR5 selective radioligand. Life Sci. 2003;73:371–379
- . Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors. J. Neurosci. 2004;24:1149–1158
- . Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-d-aspartate responses in medium spiny striatal neurons. Neuroscience. 2001;106:579–587
- . Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity. J. Neurochem. 2004;89:1479–1489
- . The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala. J. Neurosci. 2002;22:5219–5229
- . Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders. Pharmacol. Ther. 2000;88:427–435
- . Targeting adenosine A2A receptors in Parkinson's disease. Trends Neurosci. 2006;29:647–654
- . Dopamine receptors: from structure to behavior. Trends Neurosci. 2000;23:S34–S40
- . The role of dopamine in cognitive sequence learning: evidence from Parkinson's disease. Behav. Brain Res. 2005;156:191–199
- . Role of glutamate in neurodegeneration of dopamine neurons in several animal models of parkinsonism. Amino Acids. 1998;14:69–74
- . A stereotaxic atlas of the brain of the cynomolgus monkey (Macaca fascicularis). J. Comp. Neurol. 1984;222:265–300
- . Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons. J. Neurosci. 2005;25:3763–3773
PII: S0197-4580(07)00046-2
doi: 10.1016/j.neurobiolaging.2007.02.005
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 29, Issue 7
, Pages 1040-1051
, July 2008
