« Previous
Next »
Neurobiology of Aging
Volume 29, Issue 7
, Pages 992-1001
, July 2008
Aβ1–42 modulation of Akt phosphorylation via α7 nAChR and NMDA receptors
References
- . Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 2001;26(11):657–664
- . Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice. Hippocampus. 2005;15(1):110–117
- . Apolipoprotein E and beta-amyloid (1-42) regulation of glycogen synthase kinase-3beta. J. Neurochem. 2003;87(5):1152–1164
- . Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus. Neurobiol. Learn. Mem. 2002;77(3):354–371
- . Hydrogen peroxide-mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca(2+) and PI3-kinase. J. Neurochem. 2002;80(1):24–35
- . Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones. J. Neurochem. 2004;88(5):1127–1139
- . Beta-amyloid produces a delayed NMDA receptor-dependent reduction in synaptic transmission in rat hippocampus. Neuroreport. 1996;8(1):87–92
- . Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci. 2001;21(12):4125–4133
- . Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease. Neurobiol. Dis. 2001;8(1):19–31
- . CREB is a regulatory target for the protein kinase Akt/PKB. J. Biol. Chem. 1998;273(49):32377–32379
- . The cholinergic hypothesis of Alzheimer's disease: a review of progress. J. Neurol. Neurosurg. Psychiatry. 1999;66(2):137–147
- . Nicotine enhances the depressive actions of A beta 1–40 on long-term potentiation in the rat hippocampal CA1 region in vivo. J. Neurophysiol. 2003;89(6):2917–2922
- . Beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis. Eur. J. Neurosci. 2000;12(8):2735–2745
- . Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin. FASEB J. 2001;15(1):16–18
- . Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms. J. Neurosci. 2003;23(26):8967–8977
- . Long-term potentiation is increased in the CA1 area of the hippocampus of APP (swe/ind) CRND8 mice. Neurobiol. Dis. 2002;11(3):394–409
- . APP processing and synaptic function. Neuron. 2003;37(6):925–937
- . Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J. Biol. Chem. 2001;276(17):13541–13546
- . Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity. FASEB J. 2000;14(11):1508–1517
- . Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo. Eur. J. Neurosci. 2004;19(10):2839–2846
- . Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). Brain Res. Mol. Brain Res. 2002;106(1/2):94–100
- . Differential physiologic responses of alpha7 nicotinic acetylcholine receptors to beta-amyloid 1–40 and beta-amyloid 1–42. J. Neurobiol. 2003;55(1):25–30
- . Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. J. Neurosci. 2005;25(47):10960–10969
- . Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons. Neuron. 2003;38(4):611–624
- . Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation. Mol. Psychiatry. 2003;8(2):217–224
- . Enhancement of NMDA responses by beta-amyloid peptides in the hippocampus in vivo. Neuroreport. 2004;15(10):1649–1652
- . Mechanism of impairment of long-term potentiation by amyloid beta is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons. Neurosci. Lett. 2005;
- . Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms. J. Neurosci. 2003;23(9):3679–3688
- . Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. J. Neurochem. 2001;76(4):1050–1056
- . Role of protein kinase B in Alzheimer's neurofibrillary pathology. Acta Neuropathol. (Berl.). 2003;105(4):381–392
- . Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones. J. Neurochem. 2002;80(2):239–254
- . Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons. J. Neurosci. 1999;19(14):5861–5874
- . Beta-amyloid (1–42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J. Neurosci. 2001;21(1):RC120
- . State-dependent Ras signaling and AMPA receptor trafficking. Genes Dev. 2005;19(17):2000–2015
- . Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease. Neuroscience. 2003;122(1):213–228
- . Src kinases: a hub for NMDA receptor regulation. Nat. Rev. Neurosci. 2004;5(4):317–328
- . Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: role of mitogen-activated protein kinase. J. Neurochem. 1998;70(5):2082–2090
- . Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region. J. Neurosci. 2002;22(9):3359–3365
- . Alzheimer's disease: a central role for amyloid. J. Neuropathol. Exp. Neurol. 1994;53(5):438–447
- . Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 2001;81(2):741–766
- . Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1–42) amyloid. J. Biol. Chem. 2002;277(47):44920–44924
- . Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity. Biol. Psychiatry. 2001;49(3):233–239
- . Alzheimer's disease and the amyloid beta protein: what is the role of amyloid?. J. Neurochem. 1999;73(2):443–449
- . Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 2005;8(8):1051–1058
- . Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway. FASEB J. 2000;14(7):1015–1022
- . Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors. Neuroscience. 2006;137(3):795–805
- . Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J. Neurosci. 2002;22(17):7380–7388
- . Beta-amyloid(1–42) binds to alpha7 nicotinic acetylcholine receptor with high affinity, implications for Alzheimer's disease pathology. J. Biol. Chem. 2000;275(8):5626–5632
- . Amyloid peptide Abeta(1–42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors. J. Neurochem. 2000;75(3):1155–1161
- . Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J. Neurosci. 2004;24(27):6049–6056
- . Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide. Biochem. J. 2000;348(Pt 1):137–144
- . An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain. Eur. J. Neurosci. 1999;11(8):2689–2696
- . Glucose regulates glutamate-evoked arachidonic acid release from cultured striatal neurons. J. Neurochem. 1995;65(1):241–249
- . Beta-amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus. Neuroreport. 1995;6(17):2409–2413
- . Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation. J. Neurophysiol. 2004;92(5):2853–2858
PII: S0197-4580(07)00013-9
doi: 10.1016/j.neurobiolaging.2007.01.003
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 29, Issue 7
, Pages 992-1001
, July 2008
