Neurobiology of Aging
Volume 28, Issue 9 , Pages 1367-1373 , September 2007

A TGF-β1 polymorphism association with dementia and neuropathologies: The HAAS

  • Rita Peila

      Affiliations

    • Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C-309, Bethesda, 20892-9205 MD, USA
    • Pacific Health Research Institute, 846 South Hotel Street, Suite 307, Honolulu, HI 96813, USA
    • Tel.: 1 301 496 1178.
    • Tel.: 1 808 564 5420.
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 496 6292; fax: +1 301 496 4006.
  • ,
  • Berran Yucesoy

      Affiliations

    • Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, USA
    • Tel.: 1 304 285 5993.
  • ,
  • Lon R. White

      Affiliations

    • Pacific Health Research Institute, 846 South Hotel Street, Suite 307, Honolulu, HI 96813, USA
    • Department of Geriatric Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
    • Tel.: 1 808 564 5420.
    • Tel.: 1 808 564 5421.
  • ,
  • Victor Johnson

      Affiliations

    • Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, USA
    • Tel.: 1 304 285 5993.
  • ,
  • Michael L. Kashon

      Affiliations

    • Biostatistic Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
    • Tel.: 1 304 285 6209.
  • ,
  • Kim Wu

      Affiliations

    • Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C-309, Bethesda, 20892-9205 MD, USA
    • Tel.: 1 301 496 1178.
  • ,
  • Helen Petrovitch

      Affiliations

    • Pacific Health Research Institute, 846 South Hotel Street, Suite 307, Honolulu, HI 96813, USA
    • Tel.: 1 808 564 5420.
  • ,
  • Michael Luster

      Affiliations

    • Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, USA
    • Tel.: 1 304 285 5993.
  • ,
  • Lenore J. Launer

      Affiliations

    • Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C-309, Bethesda, 20892-9205 MD, USA
    • Tel.: 1 301 496 1178.

Received 27 February 2006 ,Revised 1 June 2006 ,Accepted 7 June 2006.

References 

  1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 3rd revised ed. American Psychiatric Association; 1987.
  2. Cambien F, Ricard S, Troesch A, Mallet C, Generenaz L, Evans A, et al. Polymorphisms of the transforming growth factor-beta 1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Temoin de l’Infarctus du Myocarde (ECTIM) Study. Hypertension. 1996;28(5):881–887
  3. Chui HC, Victoroff JI, Margolin D, Jagust W, Shankle R, Katzman R. Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers. Neurology. 1992;42(3 Pt 1):473–480
  4. Derynck R, Jarrett JA, Chen EY, Eaton DH, Bell JR, Assoian RK, et al. Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells. Nature. 1985;316(6030):701–705
  5. Devlin B, Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics. 1995;29(2):311–322
  6. Finch CE, Laping NJ, Morgan TE, Nichols NR, Pasinetti GM. TGF-beta 1 is an organizer of responses to neurodegeneration. J Cell Biochem. 1993;53(4):314–322
  7. Grainger DJ, Heathcote K, Chiano M, Snieder H, Kemp PR, Metcalfe JC, et al. Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet. 1999;8(1):93–97
  8. Graves ABLE, Kukull WA, et al. Screening for dementia in the community in cross-national studies: comparison between the cognitive abilities screening instrument and the mini-metanl state examination. In:  Corain BIK,  Nicolini M,  Winbald B,  Wisniewski H,  Zatta P editor. Alzheimer's disease: advances in clinical and basic research. New York, NY: John Wiley & Sons; 1993;p. 113–119
  9. Gross CE, Bednar MM, Howard DB, Sporn MB. Transforming growth factor-beta 1 reduces infarct size after experimental cerebral ischemia in a rabbit model. Stroke. 1993;24(4):558–562
  10. Gross CE, Howard DB, Dooley RH, Raymond SJ, Fuller S, Bednar MM. TGF-beta 1 post-treatment in a rabbit model of cerebral ischaemia. Neurol Res. 1994;16(6):465–470
  11. Hamaguchi T, Okino S, Sodeyama N, Itoh Y, Takahashi A, Otomo E, et al. Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy. J Neurol Neurosurg Psychiatry. 2005;76(5):696–699
  12. Havlik RJ, Izmirlian G, Petrovitch H, Ross GW, Masaki K, Curb JD, et al. APOE-epsilon4 predicts incident AD in Japanese-American men: the honolulu-asia aging study. Neurology. 2000;54(7):1526–1529
  13. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31(3):545–548
  14. Johnson VJ, Yucesoy B, Luster MI. Genotyping of single nucleotide polymorphisms in cytokine genes using real-time PCR allelic discrimination technology. Cytokine. 2004;27(6):135–141
  15. Kagan A, Popper J, Reed DM, MacLean CJ, Grove JS. Trends in stroke incidence and mortality in Hawaiian Japanese men. Stroke. 1994;25(6):1170–1175
  16. Kalaria RN. The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging. 2000;21(2):321–330
  17. Kenny D, Coughlan MG, Pagel PS, Kampine JP, Warltier DC. Transforming growth factor beta 1 preserves endothelial function after multiple brief coronary artery occlusions and reperfusion. Am Heart J. 1994;127(6):1456–1461
  18. Klempt ND, Sirimanne E, Gunn AJ, Klempt M, Singh K, Williams C, et al. Hypoxia–ischemia induces transforming growth factor beta 1 mRNA in the infant rat brain. Brain Res Mol Brain Res. 1992;13(1–2):93–101
  19. Lario S, Inigo P, Campistol JM, Poch E, Rivera F, Oppenheimer F. Restriction enzyme-based method for transforming growth factor-beta(1) genotyping: nonisotopic detection of polymorphisms in codons 10 and 25 and the 5′-flanking region. Clin Chem. 1999;45(8 Pt 1):1290–1292
  20. Luedecking EK, DeKosky ST, Mehdi H, Ganguli M, Kamboh MI. Analysis of genetic polymorphisms in the transforming growth factor-beta1 gene and the risk of Alzheimer's disease. Hum Genet. 2000;106(5):565–569
  21. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939–944
  22. McNeill H, Williams C, Guan J, Dragunow M, Lawlor P, Sirimanne E, et al. Neuronal rescue with transforming growth factor-beta 1 after hypoxic-ischaemic brain injury. Neuroreport. 1994;5(8):901–904
  23. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, et al. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991;41(4):479–486
  24. Newman AB, Sutton-Tyrrell K, Vogt MT, Kuller LH. Morbidity and mortality in hypertensive adults with a low ankle/arm blood pressure index. JAMA. 1993;270(4):487–489
  25. Newton-Cheh C, Hirschhorn JN. Genetic association studies of complex traits: design and analysis issues. Mutat Res. 2005;573(1–2):54–69
  26. Petrovitch H, Ross GW, Steinhorn SC, Abbott RD, Markesbery W, Davis D, et al. AD lesions and infarcts in demented and non-demented Japanese-American men. Ann Neurol. 2005;57(1):98–103
  27. Petrovitch H, White LR, Ross GW, Steinhorn SC, Li CY, Masaki KH, et al. Accuracy of clinical criteria for AD in the Honolulu-Asia Aging Study, a population-based study. Neurology. 2001;57(2):226–234
  28. Prehn JH, Backhauss C, Krieglstein J. Transforming growth factor-beta 1 prevents glutamate neurotoxicity in rat neocortical cultures and protects mouse neocortex from ischemic injury in vivo. J Cereb Blood Flow Metab. 1993;13(3):521–525
  29. Sugiura Y, Niimi T, Sato S, Yoshinouchi T, Banno S, Naniwa T, et al. Transforming growth factor beta1 gene polymorphism in rheumatoid arthritis. Ann Rheum Dis. 2002;61(9):826–828
  30. Suthanthiran M, Li B, Song JO, Ding R, Sharma VK, Schwartz JE, et al. Transforming growth factor-beta 1 hyperexpression in African-American hypertensives: a novel mediator of hypertension and/or target organ damage. Proc Natl Acad Sci USA. 2000;97(7):3479–3484
  31. Syme SL, Marmot MG, Kagan A, Kato H, Rhoads G. Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: introduction. Am J Epidemiol. 1975;102(6):477–480
  32. Teng EL, Hasegawa K, Homma A, Imai Y, Larson E, Graves A, et al. The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr. 1994;6(1):45–58discussion 62
  33. Vinters HV, Gilbert JJ. Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. Stroke. 1983;14(6):924–928
  34. White L, Petrovitch H, Hardman J, Nelson J, Davis DG, Ross GW, et al. Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants. Ann NY Acad Sci. 2002;977:9–23
  35. White L, Petrovitch H, Ross GW, Masaki KH, Abbott RD, Teng EL, et al. Prevalence of dementia in older Japanese-American men in Hawaii: The Honolulu-Asia Aging Study. JAMA. 1996;276(12):955–960
  36. Williams C, Guan J, Miller O, Beilharz E, McNeill H, Sirimanne E, et al. The role of the growth factors IGF-1 and TGF beta 1 after hypoxic–ischemic brain injury. Ann NY Acad Sci. 1995;765:306–307
  37. World Health Organization. Diabetes mellitus: report of a WHO study group. Geneva: WHO; 1985. Report number 727.
  38. Wyss-Coray T, Masliah E, Mallory M, McConlogue L, Johnson-Wood K, Lin C, et al. Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease. Nature. 1997;389(6651):603–606
  39. Yamada Y, Miyauchi A, Goto J, Takagi Y, Okuizumi H, Kanematsu M, et al. Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women. J Bone Miner Res. 1998;13(10):1569–1576
  40. Yokota M, Ichihara S, Lin TL, Nakashima N, Yamada Y. Association of a T29C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese. Circulation. 2000;101(24):2783–2787
  41. Yucesoy B, Peila R, White LR, Wu KM, Johnson VJ, Kashon ML, et al. Association of interleukin-1 gene polymorphisms with dementia in a community-based sample: the Honolulu-Asia Aging Study. Neurobiol Aging. 2005;

PII: S0197-4580(06)00217-X

doi: 10.1016/j.neurobiolaging.2006.06.004

Neurobiology of Aging
Volume 28, Issue 9 , Pages 1367-1373 , September 2007