Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease

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Volume 28, Issue 9 , Pages 1381-1387, September 2007

Disrupted muscarinic M₁ receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease

Shirley W.Y. Tsang
- Dementia Research Laboratory, Department of Clinical Research, Singapore General Hospital, Singapore
- Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Justine Pomakian
- Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Gad A. Marshall
- Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Harry V. Vinters
- Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Jeffrey L. Cummings
- Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Christopher P.L.-H. Chen
- Department of Neurology, National Neuroscience Institute, Singapore
Peter T.-H. Wong
- Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Mitchell K.P. Lai
- Dementia Research Laboratory, Department of Clinical Research, Singapore General Hospital, Singapore
- Correspondence to: Dementia Research Laboratory, Department of Clinical Research, Block 6, Level 6, Room B22, Singapore General Hospital, Outram Road, Singapore 169608, Singapore. Tel.: +65 6321 3731; fax: +65 6225 7796.