« Previous
Next »
Neurobiology of Aging
Volume 28, Issue 3
, Pages 357-370
, March 2007
Proteomic analysis of brain tissue from an Alzheimer's disease mouse model by two-dimensional difference gel electrophoresis
References
- . Localization and cell association of C1q in Alzheimer's disease brain. Exp Neurol. 1996;138:22–32
- . Biochemical and immunocytochemical characterization of olfactory marker protein in the rodent central nervous system. J Comp Neurol. 1989;285:246–261
- . Apolipoprotein E, amyloid, and Alzheimer disease. Mol Interv. 2002;2:363–375
- Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proc Natl Acad Sci USA. 1999;96:15233–15238
- . Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease. J Neural Transm. 1999;106:499–511
- Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice. Exp Neurol. 2003;184:247–263
- Increased fibrillar beta-amyloid in response to human clq injections into hippocampus and cortex of APP
+
PS1 transgenic mice. Neurochem Res. 2003;28:83–93 - Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons. Proc Natl Acad Sci USA. 1996;93:9858–9863
- . Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration. J Neurochem. 2003;86:1313–1327
- . Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med. 2002;32:1050–1060
- . The genetics of the amyloidoses. Annu Rev Med. 2000;51:543–569
- . Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins. Lancet. 2004;363:1139–1146
- Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med. 2002;33:562–571
- Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II. Dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. J Neurochem. 2002;82:1524–1532
- . Roles of acyl-coenzyme A: cholesterol acyltransferase-1 and -2. Curr Opin Lipidol. 2001;12:289–296
- . Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders. Mol Neurobiol. 2003;28:51–64
- . 1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities. J Biol Chem. 2000;275:28421–28427
- Structural features of rat GFAP gene and identification of a novel alternative transcript. J Neurosci Res. 1999;56:219–228
- A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease. Ann Neurol. 2005;58:277–289
- . Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein
+
presenilin-1 transgenic mice. J Neurosci. 2003;23:5219–5226 - Defective gallium-transferrin binding in Alzheimer disease and down syndrome: possible mechanism for accumulation of aluminium in brain. Lancet. 1990;335:747–750
- . Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J Neurosci. 2004;24:6457–6465
- The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell. 2001;1:515–525
- . Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann Neurol. 2000;48:77–87
- . Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem. 1966;13:655–669
- . Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522. Biochemistry. 2000;39:4267–4275
- . APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol. 1997;56:965–973
- Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci. 1997;17:7053–7059
- . Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach. Neurosci Lett. 2004;367:235–240
- . Dynamin-like protein 1 is involved in peroxisomal fission. J Biol Chem. 2003;278:8597–8605
- Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls. Am J Pathol. 2005;167:527–543
- Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. J Biol Chem. 2004;279:37061–37068
- . Proteomics in brain research: potentials and limitations. Prog Neurobiol. 2003;69:193
- . Expression of the dihydropyrimidinase related protein 2 (DRP-2) in down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level. J Neural Transm Suppl. 1999;57:161–177
- . 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage. Proc Natl Acad Sci USA. 2002;99:11599–11604
- Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. Am J Pathol. 2001;158:1345–1354
- . Shotgun proteomics and biomarker discovery. Dis Markers. 2002;18:99–105
- . GFAP: functional implications gleaned from studies of genetically engineered mice. Glia. 2003;43:87–90
- . Association of transferrin C2 allele with late-onset Alzheimer's disease. Hum Genet. 1997;101:126–129
- . In: Proceedings of the ninth international conference on Alzheimer's disease and related disorders. 2004;
- . Permeability of proteins at the blood–brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2001;8:555–567
- . Cellular and molecular biology of Alzheimer's disease and animal models. Annu Rev Med. 1994;45:435–446
- Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol. 2001;3:905–912
- Quantification of regional glial fibrillary acidic protein levels in Alzheimer's disease. Acta Neurol Scand. 2003;107:318–323
- . Proteomic analysis of the brain in Alzheimer's disease: molecular phenotype of a complex disease process. Proteomics. 2001;1:1519–1528
- . Yin and Yang: complement activation and regulation in Alzheimer's disease. Prog Neurobiol. 2003;70:463–472
- Profiling proteins related to amyloid deposited brain of Tg2576 mice. Proteomics. 2004;4:3359–3368
- . The effect of albumin on astrocyte energy metabolism is not brought about through the control of cytosolic Ca2+ concentrations but by free-fatty acid sequestration. Glia. 1999;25:1–9
- . Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging. 2002;23:485–508
- . Redox metals in Alzheimer's disease. Ann NY Acad Sci. 2004;1012:171–178
- . Proteomic profiling and neurodegeneration in Alzheimer's disease. Neurochem Res. 2002;27:1245–1253
- . Blood–brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation. 2003;10:463–470
- . Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection. Ann NY Acad Sci. 2003;992:56–71
- Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1. Mol Brain Res. 2004;132:241–259
- Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress. J Biol Chem. 2003;278:25179–25190
- . Multivalent binding of complement protein C1Q to the amyloid beta-peptide (A beta) promotes the nucleation phase of A beta aggregation. Biochem Biophys Res Commun. 1995;217:869–875
- . Amyloid angiopathy and blood-brain barrier changes in Alzheimer's disease. Ann NY Acad Sci. 1997;826:161–172
- . Therapeutic strategies for Alzheimer's disease. Nat Rev Drug Discov. 2002;1:859–866
- . The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease. CNS Drug Rev. 2004;10:127–146
- Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease. Neurobiol Dis. 2003;12:97–109
- . Up-regulated production and activation of the complement system in Alzheimer's disease brain. Am J Pathol. 1999;154:927–936
PII: S0197-4580(06)00044-3
doi: 10.1016/j.neurobiolaging.2006.01.011
© 2006 Elsevier Inc. All rights reserved.
« Previous
Next »
Neurobiology of Aging
Volume 28, Issue 3
, Pages 357-370
, March 2007
