Neurobiology of Aging
Volume 27, Issue 10 , Pages 1445-1450 , October 2006

Alzheimer-associated APP+1 transgenic mice: Frameshift β-amyloid precursor protein is secreted in cerebrospinal fluid without inducing neuropathology

  • David F. Fischer

      Affiliations

    • Netherlands Institute for Brain Research, Graduate School for Neurosciences Amsterdam, Meibergdreef 33, 1105 AZ, Amsterdam, The Netherlands
    • Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam 1081 HV, The Netherlands
    • Corresponding Author InformationCorresponding author. Present address: Galapagos Genomics, Leiden, The Netherlands. Tel.: +31 20 598 6929; fax: +31 20 598 6926.
    • ,
  • Elly M. Hol

      Affiliations

    • Netherlands Institute for Brain Research, Graduate School for Neurosciences Amsterdam, Meibergdreef 33, 1105 AZ, Amsterdam, The Netherlands
    • ,
  • Barbara Hobo

      Affiliations

    • Netherlands Institute for Brain Research, Graduate School for Neurosciences Amsterdam, Meibergdreef 33, 1105 AZ, Amsterdam, The Netherlands
    • ,
  • Fred W. van Leeuwen

      Affiliations

    • Netherlands Institute for Brain Research, Graduate School for Neurosciences Amsterdam, Meibergdreef 33, 1105 AZ, Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 20 566 5510; fax: +31 20 696 1006.

Received 23 December 2004 ,Revised 15 July 2005 ,Accepted 3 September 2005.

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PII: S0197-4580(05)00261-7

doi: 10.1016/j.neurobiolaging.2005.09.010

Neurobiology of Aging
Volume 27, Issue 10 , Pages 1445-1450 , October 2006

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