Current Issue July 2012, Vol. 33, No. 7

Issue Highlights

Postmenopausal hormone therapy, timing of initiation, APOE and cognitive decline
July 2012(Vol. 33 | No. 7 | Pages 1129-1137)
Jae H. Kang, Francine Grodstein

Hormone levels and cognitive function in postmenopausal midlife women
July 2012(Vol. 33 | No. 7 | Pages 1138-1147.e2)
Joanne Ryan, Frank Z. Stanczyk, Lorraine Dennerstein, Wendy J. Mack, Margaret S. Clark, Cassandra Szoeke, Daniel Kildea, Victor W. Henderson

Midlife memory improvement predicts preservation of hippocampal volume in old age
July 2012(Vol. 33 | No. 7 | Pages 1148-1155)
Paul R. Borghesani, Kurt E. Weaver, Elizabeth H. Aylward, Anne L. Richards, Tara M. Madhyastha, Ali R. Kahn, Olivia Liang, Rachel L. Ellenbogen, M. Faisal Beg, K. Warner Schaie, Sherry L. Willis

Age-related retinal inflammation is reduced by 670 nm light via increased mitochondrial membrane potential
18 May 2012
Ioannis Kokkinopoulos, Alan Colman, Chris Hogg, John Heckenlively, Glen Jeffery
Abstract: The mitochondrial theory of aging argues that oxidative stress, caused by mitochondrial DNA mutations, is associated with decreased adenosine triphosphate (ATP) production leading to cellula...
The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
18 May 2012
Eleanna Kara, Helen Ling, Alan M. Pittman, Karen Shaw, Rohan de Silva, Roberto Simone, Janice L. Holton, Jason D. Warren, Jonathan D. Rohrer, Georgia Xiromerisiou, Andrew Lees, John Hardy, Henry Houlden, Tamas Revesz
Abstract: Microtubule-associated protein tau (MAPT) mutations have been shown to underlie frontotemporal dementia and a variety of additional sporadic tauopathies. We identified a rare p.A152T variant...
Association between physical activity and brain health in older adults
16 May 2012
Christian Benedict, Samantha J. Brooks, Joel Kullberg, Richard Nordenskjöld, Jonathan Burgos, Madeleine Le Grevès, Lena Kilander, Elna-Marie Larsson, Lars Johansson, Håkan Ahlström, Lars Lind, Helgi B. Schiöth
Abstract: In the present cross-sectional study, we examined physical activity (PA) and its possible association with cognitive skills and brain structure in 331 cognitively healthy elderly. Based on t...
Verbal learning in Alzheimer's disease and mild cognitive impairment: fine-grained acquisition and short-delay consolidation performance and neural correlates
16 May 2012
Sarah Genon, Fabienne Collette, Chris J.A. Moulin, Françoise Lekeu, Mohamed Ali Bahri, Eric Salmon, Christine Bastin
Abstract: The aim of this study was to examine correlations between acquisition and short-delay consolidation and brain metabolism at rest measured by fluorodeoxyglucose positron emission tomography (...
Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats
16 May 2012
Wei-Na Han, Christian Hölscher, Li Yuan, Wei Yang, Xiao-Hui Wang, Mei-Na Wu, Jin-Shun Qi
Abstract: Type 2 diabetes mellitus is a risk factor of Alzheimer's disease (AD), most likely linked to an impairment of insulin signaling in the brain. Liraglutide, a novel long-lasting glucagon-like ...

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Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease
January 2012 (Vol. 33 | No. 1 | Pages 196.e29-196.e40)
Sadim Jawhar, Anna Trawicka, Carolin Jenneckens, Thomas A. Bayer, Oliver Wirths
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
January 2012 (Vol. 33 | No. 1 | Pages 197.e21-197.e32)
Brandy L. Wilkinson, Paige E. Cramer, Nicholas H. Varvel, Erin Reed-Geaghan, Qingguang Jiang, Alison Szabo, Karl Herrup, Bruce T. Lamb, Gary E. Landreth
The dynamics of Alzheimer's disease biomarkers in the Alzheimer's Disease Neuroimaging Initiative cohort
August 2010 (Vol. 31 | No. 8 | Pages 1263-1274)
A. Caroli, G.B. Frisoni, The Alzheimer's Disease Neuroimaging Initiative
The chromosome 9 ALS and FTD locus is probably derived from a single founder
January 2012 (Vol. 33 | No. 1 | Pages 209.e3-209.e8)
Kin Mok, Bryan J. Traynor, Jennifer Schymick, Pentti J. Tienari, Hannu Laaksovirta, Terhi Peuralinna, Liisa Myllykangas, Adriano Chiò, Aleksey Shatunov, Bradley F. Boeve, Adam L. Boxer, Mariely DeJesus-Hernandez, Ian R. Mackenzie, Adrian Waite, Nigel Williams, Huw R. Morris, Javier Simón-Sánchez, John C. van Swieten, Peter Heutink, Gabriella Restagno, Gabriele Mora, Karen E. Morrison, Pamela J. Shaw, Pamela Sara Rollinson, Ammar Al-Chalabi, Rosa Rademakers, Stuart Pickering-Brown, Richard W. Orrell, Michael A. Nalls, John Hardy
Role of neuroinflammation in hypertension-induced brain amyloid pathology
January 2012 (Vol. 33 | No. 1 | Pages 205.e19-205.e29)
Daniela Carnevale, Giada Mascio, Maria Antonietta Ajmone-Cat, Ivana D'Andrea, Giuseppe Cifelli, Michele Madonna, Germana Cocozza, Alessandro Frati, Pierluigi Carullo, Lorenzo Carnevale, Enrico Alleva, Igor Branchi, Giuseppe Lembo, Luisa Minghetti

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Ranked 3rd out of 44 journals in the ISI GERIATRICS & GERONTOLOGY category and 22nd out of 237 journals in the NEUROSCIENCES category!

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Neurobiology of Aging is published by Elsevier.

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About Neurobiology of Aging

Neurobiology of Aging publishes the results of studies in behavior, biochemistry, cell biology, endocrinology, molecular biology, morphology, neurology, neuropathology, pharmacology, physiology and protein chemistry in which the primary emphasis involves mechanisms of nervous system changes with age or diseases associated with age. Reviews and primary research articles are included, occasionally accompanied by open peer commentary. Letters to the Editor and brief communications are also acceptable. Brief reports of highly time-sensitive material are usually treated as rapid communications in which case editorial review is completed within six weeks and publication scheduled for the next available issue. The accepted abbreviation for Neurobiology of Aging for bibliographic citation is Neurobiol. Aging

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